越南湄公河三角洲鸡群中使用的抗菌产品的标签及质量
Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam.
作者信息
Yen Nguyen Thi Phuong, Phu Doan Hoang, Van Cuong Nguyen, Kiet Bach Tuan, Hien Be Vo, Padungtod Pawin, Truong Dinh Bao, Thwaites Guy E, Carrique-Mas Juan J
机构信息
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Sub-Department of Animal Health and Production, Cao Lanh, Dong Thap Province, Vietnam.
出版信息
Vet Med Sci. 2019 Nov;5(4):512-516. doi: 10.1002/vms3.189. Epub 2019 Aug 2.
BACKGROUND
The Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production.
METHODS
Based on a large random sample of farms, we identified the 20 most used antimicrobial products in the area, and investigated their antimicrobial active ingredient (AAI) content by UPLC-MS/MS (91 analytical tests).
RESULTS
Only 17/59 (28.8%) batches contained all AAIs within 10% of the declared strength. Worryingly, 65.0% products provided in their label preparation guidelines for both therapeutic and prophylactic use. Withdrawal times for both meat and eggs were stated in 8/20 (40%) products.
CONCLUSION
Results highlight deficiencies in quality and labelling contents that undermine authorities' efforts to discourage inappropriate use of antimicrobials.
背景
越南湄公河三角洲是抗菌药物使用（AMU）的热点地区，但关于家禽生产中使用的抗菌产品的标签质量和强度尚无相关信息。
方法
基于大量随机抽样的养殖场，我们确定了该地区使用最频繁的20种抗菌产品，并通过超高效液相色谱-串联质谱法（91次分析测试）调查了它们的抗菌活性成分（AAI）含量。
结果
只有17/59（28.8%）批次的所有AAI含量在申报强度的10%以内。令人担忧的是，65.0%的产品在其标签中提供了治疗和预防用途的配制指南。8/20（40%）的产品标明了肉类和蛋类的停药期。
结论
结果凸显了质量和标签内容方面的缺陷，这些缺陷破坏了当局为劝阻不当使用抗菌药物所做的努力。
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