Department of Pediatrics, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Child Healthcare Unit, Dubai Health Authority, Dubai, UAE.
Hum Vaccin Immunother. 2020;16(1):21-32. doi: 10.1080/21645515.2019.1638726. Epub 2019 Sep 3.
This systematic literature review was conducted to better understand the epidemiology and burden of varicella across the Middle East, gain insight into the evidence to support using universal varicella vaccination (UVV), and identify potential data gaps. Both epidemiology and economic data on the burden of varicella were limited and varied significantly. Most of the data focussed on varicella burden in the absence of a UVV program. In the absence of UVV, varicella incidence is increasing across this region with varicella infection associated with substantial morbidity. Although limited, data on the impact of vaccination at a population level indicated UVV programs reduce varicella incidence and hospitalizations, in line with global experience. Further research and action are needed to better understand varicella epidemiology in the Middle East, increase awareness and understanding in the region, and provide local data to support national public-health decisions regarding the implementation of UVV programs.
本系统文献回顾旨在更好地了解中东地区的水痘流行病学和负担，深入了解支持使用通用水痘疫苗接种（UVV）的证据，并确定潜在的数据差距。水痘的流行病学和经济负担数据都很有限且差异很大。大多数数据都集中在没有 UVV 计划的情况下水痘负担。在没有 UVV 的情况下，该地区的水痘发病率正在上升，水痘感染与大量发病率有关。尽管数据有限，但在人群层面上接种疫苗的影响数据表明，UVV 计划可降低水痘发病率和住院率，与全球经验一致。需要进一步研究和采取行动，以更好地了解中东地区的水痘流行病学，提高该地区的认识和理解，并提供本地数据，以支持国家公共卫生决策，实施 UVV 计划。
