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反复颅周神经阻滞在慢性阵发性偏侧头痛的治疗中是否有效?:一例病例报告。

Are repetitive pericranial nerve blocks effective in the management of chronic paroxysmal hemicrania?: A case report.

作者信息

Ertem Devrimsel Harika

机构信息

Department of Neurology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

出版信息

Medicine (Baltimore). 2019 Aug;98(31):e16484. doi: 10.1097/MD.0000000000016484.

Abstract

INTRODUCTION

Paroxysmal hemicrania (PH) is a chronic headache disorder characterized by unilateral pain attacks accompanied by cranial autonomic symptoms and responds to indomethacin completely. There are few alternative treatment options for the patients who cannot tolerate indomethacin. Studies exploring the effects of repetitive peripheral cranial nerve blocks in the management of chronic PH are limited.

PATIENT CONCERNS AND DIAGNOSIS

A 34-year-old woman with a 4-year history of PH was evaluated. Her pain was prevented by indomethacin without side effects; however, she wanted to try to conceive.

INTERVENTIONS

Repetitive pericranial nerve blocks, great occipital nerve, infraorbital nerve, supraorbital nerve, and sphenopalatine ganglion block, using local anesthetics and steroids were performed once a week for a 6 weeks period.

OUTCOMES

A follow-up of 3 months showed that there was no pain relief following the injections and patient was needed to be maintained on indomethacin.

CONCLUSION

Although pericranial nerve blocks have been tried in chronic PH cases with positive influences, this case indicated that repetitive nerve blocks were not always a successful therapy option.

摘要

引言

发作性偏侧头痛(PH)是一种慢性头痛疾病,其特征为单侧疼痛发作并伴有颅自主神经症状,且对消炎痛完全有效。对于不能耐受消炎痛的患者,几乎没有其他治疗选择。探索重复性外周颅神经阻滞在慢性PH治疗中的作用的研究有限。

患者情况与诊断

评估了一名有4年PH病史的34岁女性。她的疼痛可通过消炎痛缓解且无副作用;然而,她想要尝试怀孕。

干预措施

使用局部麻醉剂和类固醇进行重复性颅周神经阻滞,包括枕大神经、眶下神经、眶上神经和蝶腭神经节阻滞,每周进行一次,共持续6周。

结果

3个月的随访显示,注射后疼痛未缓解,患者仍需使用消炎痛维持治疗。

结论

尽管在慢性PH病例中尝试过颅周神经阻滞且有积极影响,但该病例表明重复性神经阻滞并不总是成功的治疗选择。

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本文引用的文献

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Ann Indian Acad Neurol. 2018 Apr;21(Suppl 1):S16-S22. doi: 10.4103/aian.AIAN_317_17.
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Indomethacin in pregnancy: applications and safety.妊娠期间使用吲哚美辛:应用与安全性。
Am J Perinatol. 2012 Mar;29(3):175-86. doi: 10.1055/s-0031-1284227. Epub 2011 Jul 22.
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