Departamento Micología, INEI "Dr. Carlos G. Malbrán", Buenos Aires, Argentina.
Instituto de Zoonosis "Luis Pasteur", Buenos Aires, Argentina.
Mycopathologia. 2019 Oct;184(5):701-706. doi: 10.1007/s11046-019-00368-1. Epub 2019 Aug 2.
Mycelial basidiomycetes rarely produce mycoses in animals including humans. We report a case of a 9-year-old female mongrel dog with lesions in the prescapular lymph nodes. The histopathology of a lymph node sample showed flexuous septate hyphae, and a sterile mold grew in culture from that specimen. DNA sequencing of the ITS region allowed us to identify the fungus as Tropicoporus tropicalis. The dog was treated with itraconazole, but it was euthanized six months later due to an unfavorable clinical outcome. Tropicoporus tropicalis is an infrequent pathogen of pets, and the use of molecular tools is needed for its identification. Animal infections due to T. tropicalis were not previously been reported in Argentina.
担子菌的菌丝体很少在包括人类在内的动物中引起真菌感染。我们报告了一例 9 岁雌性杂种犬,其肩胛前淋巴结有病变。淋巴结样本的组织病理学显示弯曲的有隔菌丝,从该标本中培养出无菌霉菌。ITS 区的 DNA 测序使我们能够鉴定出这种真菌为热带多孔菌。该犬接受了伊曲康唑治疗,但由于临床预后不佳,六个月后被安乐死。热带多孔菌是宠物的一种不常见病原体,需要使用分子工具进行鉴定。在阿根廷,以前没有报道过热带多孔菌引起的动物感染。