特发性间质性肺炎伴自身免疫特征。

Interstitial Pneumonia with Autoimmune Features.

机构信息

Divisions of Rheumatology, Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, University of Colorado School of Medicine, 12631 East 17th Avenue, Academic Office Building One, Aurora, CO 80045, USA.

出版信息

Clin Chest Med. 2019 Sep;40(3):609-616. doi: 10.1016/j.ccm.2019.05.007.

DOI:10.1016/j.ccm.2019.05.007

PMID:31376895

Abstract

The European Respiratory Society/American Thoracic Society Task Force on Undifferentiated Forms of Connective Tissue Disease-associated Interstitial Lung Disease put forth the research classification interstitial pneumonia with autoimmune features as a step toward uniformly describing these patients. Diverse nomenclature and classification schemes had been proposed to characterize them. This classification has provided uniform nomenclature and criteria, fostering interdisciplinary engagement and research. Longitudinal surveillance is needed; some patients evolve to a defined connective tissue disease. This review discusses cohort studies of interstitial pneumonia with autoimmune features and what they have taught us about the phenotype, and offers insights into future directions.

摘要

欧洲呼吸学会/美国胸科学会特发性结缔组织疾病相关性间质性肺疾病工作组提出了自身免疫特征性间质性肺炎的研究分类，以统一描述这些患者。曾提出过多种命名法和分类方案来对其进行描述。该分类为这些患者提供了统一的命名法和标准，促进了跨学科的参与和研究。需要进行纵向监测；一些患者会发展为明确的结缔组织疾病。本文综述了自身免疫特征性间质性肺炎的队列研究，以及它们在表型方面为我们提供的信息，并对未来的方向提出了见解。