Yan H, Wu X Y, Dang S N, Zhang Y D, Luo S Y
The Children's Hospital, Zhengzhou University, Zhengzhou 450018, China.
School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Aug 6;53(8):829-834. doi: 10.3760/cma.j.issn.0253-9624.2019.08.006.
To analyze the types of dietary patterns of women during pregnancy in Shaanxi and their association with adverse pregnancy outcomes. Data were derived from a cross-sectional program named "The prevalence and risk factors of birth defects in Shaanxi Province" from July to November in 2013. A multi-stage stratified random sampling method was used to extract 15 980 women of childbearing age who met the inclusion exclusion criteria from Shaanxi Province. The questionnaire obtained information such as the pregnancy outcome and the food intake of the study subjects during pregnancy. The dietary pattern was extracted by factor analysis, and the each dietary pattern of subjects were divided into (1)-(3) groups according to the factor score. The effects of each dietary pattern on major adverse pregnancy outcomes were estimated by unconditional logistic regression model. Four dietary patterns were established:vegetarian pattern, balanced pattern, traditional pattern, and processing pattern. The multivariate logistic regression model results showed that compared with the vegetarian pattern (2) group, the (1) group had lower risk of low birth weight (0.56, 95: 0.41-0.83), and the (3) group had higher risk of low birth weight in offspring (2.32, 95: 1.59-3.89); compared with the traditional pattern (2) group, the (3) group had higher risk of premature (2.62, 95: 1.58-5.01); compared with the balanced pattern (2) group, the (3) group had a lower risk of spontaneous abortion (0.73, 95: 0.36-0.89); compared with the processing pattern (2) group, the (3) group had a higher risk of spontaneous abortion (1.97, 95: 1.36-3.34) and higher risk of stillbirth (2.96, 95: 1.49-6.26), and the (1) group had a lower risk of stillbirths in offspring (0.52, 95: 0.33-0.83). The women of childbearing age in Shaanxi have different dietary patterns, and there may be a correlation between dietary patterns and adverse pregnancy outcomes.
分析陕西省孕期女性的饮食模式类型及其与不良妊娠结局的关联。数据来源于2013年7月至11月开展的一项名为“陕西省出生缺陷患病率及危险因素”的横断面项目。采用多阶段分层随机抽样方法,从陕西省抽取15980名符合纳入排除标准的育龄妇女。通过问卷调查获取研究对象的妊娠结局及孕期食物摄入等信息。采用因子分析法提取饮食模式,并根据因子得分将研究对象的各饮食模式分为(1)-(3)组。采用非条件logistic回归模型估计各饮食模式对主要不良妊娠结局的影响。建立了四种饮食模式:素食模式、均衡模式、传统模式和加工食品模式。多因素logistic回归模型结果显示,与素食模式(2)组相比,(1)组低出生体重风险较低(0.56,95%CI:0.41-0.83),(3)组后代低出生体重风险较高(2.32,95%CI:1.59-3.89);与传统模式(2)组相比,(3)组早产风险较高(2.62,95%CI:1.58-5.01);与均衡模式(2)组相比,(3)组自然流产风险较低(0.73,95%CI:0.36-0.89);与加工食品模式(2)组相比,(3)组自然流产风险较高(1.97,95%CI:1.36-3.34),死产风险较高(2.96,95%CI:1.49-6.26),(1)组后代死产风险较低(0.52,95%CI:0.33-0.83)。陕西省育龄妇女存在不同的饮食模式,饮食模式与不良妊娠结局之间可能存在相关性。