POFUT1 and PLAGL2 gene pair linked by a bidirectional promoter: the two in one of tumour progression in colorectal cancer?
作者信息
Germot Agnès, Maftah Abderrahman
机构信息
Limoges University, PEIRENE, EA 7500, Glycosylation and Cell Differentiation, F-87060 Limoges, France.
Limoges University, PEIRENE, EA 7500, Glycosylation and Cell Differentiation, F-87060 Limoges, France.
出版信息
EBioMedicine. 2019 Aug;46:25-26. doi: 10.1016/j.ebiom.2019.07.065. Epub 2019 Aug 1.
Abstract
摘要
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POFUT1 and PLAGL2 gene pair linked by a bidirectional promoter: the two in one of tumour progression in colorectal cancer?由双向启动子连接的POFUT1和PLAGL2基因对：二者合一在结直肠癌肿瘤进展中的作用？
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本文引用的文献
1
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.PLAGL2 和 POFUT1 受一个进化上保守的双向启动子调控，通过维持干细胞特性协同参与结直肠癌的发生。
EBioMedicine. 2019 Jul;45:124-138. doi: 10.1016/j.ebiom.2019.06.051. Epub 2019 Jul 4.
2
Overexpressed PLAGL2 transcriptionally activates Wnt6 and promotes cancer development in colorectal cancer.过表达的 PLAGL2 转录激活 Wnt6 并促进结直肠癌的癌症发生。
Oncol Rep. 2019 Feb;41(2):875-884. doi: 10.3892/or.2018.6914. Epub 2018 Dec 7.
3
as a Promising Novel Biomarker of Colorectal Cancer.作为一种有前景的结直肠癌新型生物标志物。
Cancers (Basel). 2018 Oct 30;10(11):411. doi: 10.3390/cancers10110411.
4
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.POFUT1 通过激活 Notch1 信号促进结直肠癌的发展。
Cell Death Dis. 2018 Sep 24;9(10):995. doi: 10.1038/s41419-018-1055-2.
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Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.破解边缘介导的Notch密码：识别允许区分配体的激活和抑制位点。
Dev Cell. 2017 Jan 23;40(2):193-201. doi: 10.1016/j.devcel.2016.12.013. Epub 2017 Jan 12.
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Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.转铁蛋白受体1的非经典作用对肠道稳态至关重要。
Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11714-9. doi: 10.1073/pnas.1511701112. Epub 2015 Aug 31.
7
The role of pleomorphic adenoma gene-like 2 in gastrointestinal cancer development, progression, and prognosis.多形性腺瘤样基因2在胃肠道癌发生、发展及预后中的作用
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