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Editorial: Genetic Modification of Cardiac Tissue.

作者信息

Camara Amadou K S, Stowe David F, O-Uchi Jin, Bazil Jason N

机构信息

Departments of Anesthesiology and Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.

Cardiovascular Division, Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, United States.

出版信息

Front Cardiovasc Med. 2019 Jul 16;6:93. doi: 10.3389/fcvm.2019.00093. eCollection 2019.

DOI:10.3389/fcvm.2019.00093
PMID:31380395
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6646414/
Abstract
摘要

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本文引用的文献

1
Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.心血管代谢风险位点在不同组织和疾病中共享下游顺式和反式基因调控。
Science. 2016 Aug 19;353(6301):827-30. doi: 10.1126/science.aad6970.
2
A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation.一种人类先天性心脏病的小鼠模型：杂合性Nkx2-5同源结构域错义突变导致多种心脏异常和心室致密化不全的高发生率。
Circ Cardiovasc Genet. 2014 Aug;7(4):423-433. doi: 10.1161/CIRCGENETICS.113.000281. Epub 2014 Jul 15.
3
Cardiovascular genetics: paying individual dividends.心血管遗传学：获取个体收益。
Sci Transl Med. 2014 Jun 4;6(239):239ed12. doi: 10.1126/scitranslmed.3008854.
4
Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability.体内 BK 电流的遗传激活对神经元兴奋性产生双向影响。
Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18997-9002. doi: 10.1073/pnas.1205573109. Epub 2012 Oct 29.