Abbasain Hamideh, Sadeghi Ramin, Emami Farshad, Dabbagh Kakhki Vahid Reza
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Nuclear Medicine and , Department of Molecular Imaging, Imam Reza International University, Mashhad, Iran.
Asia Ocean J Nucl Med Biol. 2019 Spring;7(2):181-184. doi: 10.22038/AOJNMB.2019.13360.
Carcinosarcoma is a rare type of cancer that is composed of a mixture of sarcomatous and carcinomatous elements. Pulmonary carcinosarcoma has a 25% five-year survival rate with a prognosis poorer than other non-small cell lung carcinomas. Herein, we report a case of pulmonary carcinosarcoma and its F-FDG PET/CT findings. A 61-year-old male patient presented with brain symptoms, including headache, nausea, right hemiplegia, and few attacks of seizures. He underwent brain computed tomography (CT) scan showing a brain lesion in the left parietal lobe. The patient underwent excisional biopsy, and brain lesion was removed. The results of tissue sampling were indicative of carcinosarcoma. Based on anatomical imaging and evidence of pulmonary lesion, the patient underwent FDG PET/CT that revealed a heterogeneous mass on the upper lobe of the left lung. An intense FDG uptake was observed along the rim of the mass; however, no FDG uptake was observed in the center of the mass. There were multiple mediastinal lymph nodes with a high FDG uptake. Pulmonary carcinosarcoma was confirmed by tissue sampling.
癌肉瘤是一种罕见的癌症类型，由肉瘤样和癌样成分混合组成。肺癌肉瘤的五年生存率为25%，预后比其他非小细胞肺癌更差。在此，我们报告一例肺癌肉瘤及其F-FDG PET/CT表现。一名61岁男性患者出现脑部症状，包括头痛、恶心、右侧偏瘫和几次癫痫发作。他接受了脑部计算机断层扫描（CT），显示左顶叶有一个脑部病变。患者接受了切除活检，脑部病变被切除。组织取样结果显示为癌肉瘤。基于解剖学成像和肺部病变证据，患者接受了FDG PET/CT检查，结果显示左肺上叶有一个不均匀肿块。在肿块边缘观察到强烈的FDG摄取；然而，在肿块中心未观察到FDG摄取。有多个纵隔淋巴结有高FDG摄取。通过组织取样确诊为肺癌肉瘤。
