Garrido-Miguel Miriam, Cavero-Redondo Iván, Álvarez-Bueno Celia, Rodríguez-Artalejo Fernando, Moreno Luis A, Ruiz Jonatan R, Ahrens Wolfgang, Martínez-Vizcaíno Vicente
Universidad de Castilla-La Mancha, Health and Social Research Center, Cuenca, Spain.
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, IdiPaz, Madrid, Spain.
JAMA Pediatr. 2019 Oct 1;173(10):e192430. doi: 10.1001/jamapediatrics.2019.2430. Epub 2019 Oct 7.
Studies of trends in excess weight among European children throughout the last few decades have rendered mixed results. Additionally, some studies were outdated, were based on self-reported weight and height, or included only a few European countries.
To assess prevalence trends in measured overweight and obesity among children across Europe from 1999 to 2016 using a systematic methodology.
MEDLINE, Embase, CINAHL, and Web of Science were searched from their inception until May 2018. Moreover, searches were conducted on health institutions' websites to identify studies not published in scientific journals.
The inclusion criteria were: (1) studies reporting the population-based prevalence of excess weight (overweight plus obesity) or obesity according to body mass index cutoffs proposed by the International Obesity Task Force; (2) cross-sectional or follow-up studies; and (3) studies including populations aged 2 to 13 years.
Literature review and data extraction followed established guidelines. The Mantel-Haenszel method was used to compute the pooled prevalence estimates and their 95% CI whenever there was no evidence of heterogeneity (I2 < 50%); otherwise, the DerSimonian and Laird random-effects method was used. Subgroup analyses by study year, country, or European region (Atlantic, Iberian, Central, and Mediterranean) were conducted. Prevalence estimates were calculated as an aggregate mean, weighted by the sample size and the number of individuals in each study.
A total of 103 studies (477 620 children aged 2 to 13 years) with data from 28 countries were included. The combined prevalence of overweight and obesity in the Iberian region tended to decrease from 30.3% (95% CI, 28.3%-32.3%) to 25.6% (95% CI, 19.7%-31.4%) but tended to increase in the Mediterranean region from 22.9% (95% CI, 17.9%-27.9%) to 25.0% (95% CI, 14.5%-35.5%). No substantial changes were observed in Atlantic Europe or Central Europe, where the overweight and obesity prevalence changed from 18.3% (95% CI, 14.0%-23.9%) to 19.3% (95% CI, 17.7%-20.9%) and from 15.8% (95% CI, 13.4%-18.5%) to 15.3% (95% CI, 11.6%-20.3%), respectively.
The prevalence of childhood overweight and obesity is very high, but trends have stabilized in most European countries. There are substantial between-country differences in the current levels and trends of overweight and obesity. The rising prevalence in some Mediterranean countries is worrisome.
PROSPERO identifier: CRD42017056924.
过去几十年间,对欧洲儿童超重趋势的研究结果不一。此外,一些研究已过时,基于自我报告的体重和身高,或仅涵盖少数欧洲国家。
采用系统方法评估1999年至2016年欧洲儿童实测超重和肥胖的患病率趋势。
检索MEDLINE、Embase、CINAHL和科学网,时间跨度从各数据库创建至2018年5月。此外,还在卫生机构网站上进行检索,以识别未发表在科学期刊上的研究。
纳入标准为:(1)根据国际肥胖问题工作组提出的体重指数临界值报告基于人群的超重(超重加肥胖)或肥胖患病率的研究;(2)横断面研究或随访研究;(3)纳入2至13岁人群的研究。
文献综述和数据提取遵循既定指南。只要没有异质性证据(I2<50%),就使用Mantel-Haenszel方法计算合并患病率估计值及其95%置信区间;否则,使用DerSimonian和Laird随机效应方法。按研究年份、国家或欧洲区域(大西洋、伊比利亚、中部和地中海)进行亚组分析。患病率估计值以汇总均值计算,按样本量和每项研究中的个体数量加权。
共纳入103项研究(477620名2至13岁儿童),数据来自28个国家。伊比利亚地区超重和肥胖的合并患病率从30.3%(95%置信区间,28.3%-32.3%)呈下降趋势,降至25.6%(95%置信区间,19.7%-31.4%),但地中海地区则从22.9%(95%置信区间,17.9%-27.9%)呈上升趋势,升至25.0%(95%置信区间,14.5%-35.5%)。在大西洋欧洲或中欧未观察到实质性变化,超重和肥胖患病率分别从18.3%(95%置信区间,14.0%-23.9%)变为19.3%(95%置信区间,17.7%-20.9%),从15.8%(95%置信区间,13.4%-18.5%)变为15.3%(95%置信区间,11.6%-20.3%)。
儿童超重和肥胖的患病率很高,但在大多数欧洲国家趋势已趋于稳定。超重和肥胖的当前水平及趋势在各国之间存在显著差异。一些地中海国家患病率的上升令人担忧。
PROSPERO标识符:CRD42017056924。