Gorgiladze G I
Biull Eksp Biol Med. 1979 Jul;88(7):21-3.
The role of spinal afferentation from the lower part of the body in establishing compensation of the consequences of the vestibular function abaissement was studied in experiments on guinea pigs. The ligation of the spinal cord at the level of thoracic segements performed under local anesthesia neither produced appreciable effect on the compensatory development at simultaneous or subsequent destruction of the labyrinth nor destroyed it in the preliminarily labyrinthectomized animals. The ligation of the spinal cord in the labyrinthectomized animals under ether or chloroform anesthesia was accompanied by a strong disorder of the compensation. The above substances also provoked analogous decompensation in the unilaterally labyrinthectomized animals with an intact spinal cord. The results obtained indicate that the reported disorder of the vestibular compensation induced by ligation of the spinal cord under ether anesthesia is consequent on an immediate effect of inhalation anesthetics on the compensatory mechanisms rather than is resultant of abolishing spinal afferentation from the lower part of the body.
在豚鼠实验中，研究了来自身体下部的脊髓传入在建立前庭功能减退后果的代偿中的作用。在局部麻醉下于胸段水平结扎脊髓，对同时或随后破坏迷路时的代偿发育均未产生明显影响，也未在预先进行迷路切除的动物中破坏代偿。在乙醚或氯仿麻醉下对迷路切除动物结扎脊髓，会伴随代偿的强烈紊乱。上述物质在脊髓完整的单侧迷路切除动物中也引发类似的失代偿。所获结果表明，在乙醚麻醉下结扎脊髓所致的前庭代偿紊乱是吸入麻醉药对代偿机制的直接作用所致，而非身体下部脊髓传入被阻断的结果。
