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本文引用的文献

1
Role of surgery in pancreatic neuroendocrine tumor.手术在胰腺神经内分泌肿瘤中的作用。
Gland Surg. 2018 Feb;7(1):36-41. doi: 10.21037/gs.2017.12.05.
2
Surveillance strategy for small asymptomatic non-functional pancreatic neuroendocrine tumors - a systematic review and meta-analysis.小的无症状非功能性胰腺神经内分泌肿瘤的监测策略——一项系统评价和荟萃分析
HPB (Oxford). 2017 Apr;19(4):310-320. doi: 10.1016/j.hpb.2016.12.010. Epub 2017 Feb 21.
3
Nonhypervascular Pancreatic Neuroendocrine Tumors: Differential Diagnosis from Pancreatic Ductal Adenocarcinomas at MR Imaging-Retrospective Cross-sectional Study.非富血供胰腺神经内分泌肿瘤：MR 成像鉴别诊断胰腺导管腺癌——一项回顾性横断面研究。
Radiology. 2017 Jul;284(1):77-87. doi: 10.1148/radiol.2016160586. Epub 2017 Jan 13.
4
Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis.胰腺神经内分泌肿瘤与实性假乳头状肿瘤：鉴别诊断的关键免疫组化特征
World J Gastroenterol. 2016 Oct 14;22(38):8596-8604. doi: 10.3748/wjg.v22.i38.8596.
5
Pancreatic tumors in children and young adults with tuberous sclerosis complex.患有结节性硬化症的儿童和年轻成人的胰腺肿瘤。
Pediatr Radiol. 2017 Jan;47(1):39-45. doi: 10.1007/s00247-016-3701-0. Epub 2016 Sep 17.
6
ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors.《欧洲神经内分泌肿瘤学会功能性胰腺神经内分泌肿瘤和非功能性胰腺神经内分泌肿瘤患者管理共识指南更新》
Neuroendocrinology. 2016;103(2):153-71. doi: 10.1159/000443171. Epub 2016 Jan 5.
7
Can pancreatic neuroendocrine tumour biopsy accurately determine pathological characteristics?胰腺神经内分泌肿瘤活检能否准确确定病理特征？
Dig Liver Dis. 2015 Nov;47(11):973-7. doi: 10.1016/j.dld.2015.06.005. Epub 2015 Jun 20.
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Cystic pancreatic neuroendocrine tumors: To date a diagnostic challenge.胰腺囊性神经内分泌肿瘤：迄今为止仍是诊断难点。
Int J Surg. 2015 Sep;21 Suppl 1:S44-9. doi: 10.1016/j.ijsu.2015.04.087. Epub 2015 Jun 26.
9
Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 Iinternational Tuberous Sclerosis Complex Consensus Conference.结节性硬化症综合诊断标准更新：2012 年国际结节性硬化症共识会议推荐。
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Pancreatic neuroendocrine tumors: biology, diagnosis,and treatment.胰腺神经内分泌肿瘤：生物学、诊断与治疗
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结节性硬化背景下的有趣胰腺肿瘤。

Interesting pancreatic tumour in the background of Tuberous Sclerosis.

作者信息

Amarjothi Jmv, Jesudason Jeyasudhahar, Ramasamy Villalan, Babu Ol Naganath

机构信息

Department of Surgical Gastroenterology, Madras Medical College and Government General Hospital, Chennai, Tamil Nadu, India.

Department of Surgical Gastroenterology, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India.

出版信息

BMJ Case Rep. 2019 Aug 4;12(8):e227292. doi: 10.1136/bcr-2018-227292.

DOI:10.1136/bcr-2018-227292
PMID:31383671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6685411/
Abstract

Tuberous Sclerosis Complex (TSC) is easily discernible by a myriad of manifestations, most notably dermatological. It is associated with well known and recognised intra-abdominal tumours like angiomyolipoma of the kidney. However, rarer tumours like pancreatic neuroendocrine tumours can occur in the setting of TSC. A high index of suspicion is necessary to identify and treat these lesions early in their natural course. Early identification augurs well with complete surgical excision and excellent survival.

摘要

结节性硬化症（TSC）很容易通过多种表现被识别出来，最显著的是皮肤方面的表现。它与诸如肾血管平滑肌脂肪瘤等广为人知且公认的腹腔内肿瘤有关。然而，像胰腺神经内分泌肿瘤这样较罕见的肿瘤也可能在TSC的情况下发生。在这些病变的自然病程早期识别并治疗它们，需要高度的怀疑指数。早期识别有利于完整的手术切除和良好的生存率。