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[治疗依从性:慢性血液透析患者面临的另一项挑战]

[Therapeutic compliance: another challenge for patients on chronic haemodialysis].

作者信息

Mhammedi Saad Alaoui, Hamdi Fathia, Benabdelhak Mohammed, Bentata Yassamine, Haddiya Intissar

机构信息

Centre Hospitalier Universitaire Mohammed VI, Oujda, Maroc.

出版信息

Pan Afr Med J. 2019 May 15;33:28. doi: 10.11604/pamj.2019.33.28.9448. eCollection 2019.

DOI:10.11604/pamj.2019.33.28.9448
PMID:31384343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6658161/
Abstract

Poor compliance with therapy is frequently encountered in most of patients with chronic diseases. It increases the risk of morbi-mortality and healthcare costs. Patients on chronic haemodialysis often have poor compliance with treatment. This study aims to assess the level of compliance with treatment in our patients on chronic hemodialysis and to identify the predictive factors of poor compliance with treatment. We conducted a cross-sectional study at the Oujda Hospital in November 2011. The compliance with treatment was measured using a questionnaire: the compliance evaluation test (CET) assessed the compliance with medication treatment and diet. A rate of 85% was retained arbitrarily as a threshold for good compliance with treatment. Patient in a zone of partial adherence had a rate between 57% and 85% while a lower rate (57%) indicated poor compliance with treatment. Different demographic and clinicobiologic parameters were analyzed and predictive factors for good and poor compliance with treatment were identified. Our study involved 101 patients on chronic haemodialysis; the sex ratio was 1.2, the average age of patients was 15.6 years. CET showed that 23.4% of patients had good compliance with treatment, 39.4% partial compliance with treatment and 37.2% poor compliance with treatment. Statistical analysis showed that poor compliance with treatment was associated with a lower socio-economic and intellectual status, with co-morbidities and with long term hemodialysis. Good compliance with treatment was observed in very old patients helped by a third person, taking a reduced number of medications, with a higher intellectual level.

摘要

大多数慢性病患者经常出现治疗依从性差的情况。这增加了发病死亡率和医疗成本的风险。接受慢性血液透析的患者通常治疗依从性较差。本研究旨在评估我们医院接受慢性血液透析患者的治疗依从性水平,并确定治疗依从性差的预测因素。2011年11月,我们在乌季达医院进行了一项横断面研究。使用一份问卷来衡量治疗依从性:依从性评估测试(CET)评估药物治疗和饮食的依从性。任意设定85%的比率作为治疗依从性良好的阈值。处于部分依从区域的患者比率在57%至85%之间,而较低的比率(57%)表明治疗依从性差。分析了不同的人口统计学和临床生物学参数,并确定了治疗依从性良好和差的预测因素。我们的研究纳入了101例接受慢性血液透析的患者;性别比为1.2,患者平均年龄为15.6岁。CET显示,23.4%的患者治疗依从性良好,39.4%的患者部分依从,37.2%的患者依从性差。统计分析表明,治疗依从性差与较低的社会经济和智力水平、合并症以及长期血液透析有关。在由第三人协助、服用药物数量较少、智力水平较高的高龄患者中观察到治疗依从性良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82e/6658161/e46c38a5084e/PAMJ-33-28-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82e/6658161/e46c38a5084e/PAMJ-33-28-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82e/6658161/e46c38a5084e/PAMJ-33-28-g001.jpg

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