Weber Marianne F, Marshall Henry M, Rankin Nicole, Duffy Stephen, Fong Kwun M, Dunlop Kate, Humphries Lauren, Smit Amelia K, Cust Anne E, Taylor Natalie, Mitchell Gillian, Kang Yoon-Jung, Tucker Kathy, Jenkins Mark, Macrae Finlay, Lockart Ian, Danta Mark, Armstrong Bruce K, Howe Megan
Cancer Research Division, Cancer Council NSW, Sydney, Australia; School of Public Health, University of Sydney, NSW, Australia.
Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, QLD, Australia; University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, Australia.
Public Health Res Pract. 2019 Jul 31;29(2):2921910. doi: 10.17061/phrp2921910.
While Australia now has well-established national screening programs for breast, bowel and cervical cancers, research continues into the feasibility of developing systematic screening programs for a number of other cancers. In this paper, experts in their fields provide perspectives on the current state of play and future directions for screening and surveillance for melanoma, Lynch syndrome, and liver, lung and prostate cancers in Australia. Although the evidence does not support population screening, there may be opportunities to prevent thousands of deaths through systematic approaches to the early detection of lung cancer and melanoma, testing for Lynch syndrome, and organised surveillance for hepatocellular carcinoma among individuals at high risk - guided by targeted research. The paper also looks at what impact new prostate specific antigen testing guidelines are having on screening for prostate cancer.
虽然澳大利亚目前已有完善的乳腺癌、肠癌和宫颈癌国家筛查项目，但对于开展其他多种癌症的系统筛查项目的可行性研究仍在继续。在本文中，各领域专家就澳大利亚黑色素瘤、林奇综合征以及肝癌、肺癌和前列腺癌的筛查与监测现状及未来方向发表了看法。尽管现有证据不支持进行人群筛查，但通过对肺癌和黑色素瘤进行早期检测、林奇综合征检测以及对高危个体进行肝细胞癌的有组织监测的系统方法（以针对性研究为指导），可能有机会预防数千例死亡。本文还探讨了新的前列腺特异性抗原检测指南对前列腺癌筛查产生的影响。
