Drapeau Annie, Walz Patrick C, Eide Jacob G, Rugino Alex J, Shaikhouni Ammar, Mohyeldin Ahmed, Carrau Ricardo L, Prevedello Daniel M
Department of Pediatric Neurosurgery, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Childs Nerv Syst. 2019 Nov;35(11):2133-2145. doi: 10.1007/s00381-019-04300-2. Epub 2019 Aug 5.
Craniopharyngioma has historically been recognized to be a formidable pathology primarily due to its proximity to critical neurovascular structures and the challenging surgical corridors that surgeons have tried to reach this lesion.
In this work, we review the medical and surgical management of these tumors with a focus on clinical presentation, diagnostic identification, surgical approach, and associated adjuvant therapies. We will also discuss our current treatment paradigm using endoscopic, open, and combined approaches to craniopharyngiomas. The management of craniopharyngiomas requires a multidisciplinary team of surgeons, endocrinologists, and neuroanesthesiologists as well as neurocritical care specialists to deliver the most comprehensive and safest surgical resection with minimal postoperative morbidity.
颅咽管瘤在历史上一直被认为是一种棘手的病理疾病,主要是因为它靠近关键的神经血管结构,以及外科医生试图到达该病变时面临的具有挑战性的手术通道。
在这项工作中,我们回顾了这些肿瘤的内科和外科治疗,重点关注临床表现、诊断识别、手术方法和相关辅助治疗。我们还将讨论我们目前使用内镜、开放和联合方法治疗颅咽管瘤的治疗模式。颅咽管瘤的管理需要外科医生、内分泌学家、神经麻醉师以及神经重症监护专家组成的多学科团队,以实现最全面、最安全的手术切除,并将术后发病率降至最低。