Endocrinology Unit, Policlinico San Martino, Genoa, 16132, Italy.
Pathology, Department of Integrated Surgical & Diagnostic Sciences, University of Genoa, Genoa, 16132, Italy.
Future Oncol. 2019 Aug;15(24s):13-19. doi: 10.2217/fon-2019-0099. Epub 2019 Aug 6.
We report a case of an elderly woman presenting with a huge cervical mass invading the tracheal lumen. Diagnosed as invasive poorly differentiated thyroid cancer, after an endotracheal biopsy, stenting and radiotherapy, it was judged eligible for total thyroidectomy, but surgery was delayed due to pulmonary thromboembolism. The patient was therefore treated with lenvatinib with a neoadjuvant intent until hemodynamic stability was obtained. Thyroidectomy and radioiodine therapy were then performed and the postdose scan revealed an area of modest uptake in the anterior part of the neck. The patient is now in a good clinical status and she continues her follow-up program without any adjuvant therapy.
我们报告了一例老年女性患者，其表现为巨大的颈椎肿块侵犯气管腔。诊断为侵袭性低分化甲状腺癌，在进行气管内活检、支架置入和放疗后，认为适合进行全甲状腺切除术，但由于肺血栓栓塞症而延迟了手术。因此，该患者使用仑伐替尼进行新辅助治疗，直到血流动力学稳定。随后进行了甲状腺切除术和放射性碘治疗，术后扫描显示颈部前部有一个适度摄取区域。目前患者临床状况良好，她继续接受随访，无需辅助治疗。
