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[特定维生素、矿物质及抗氧化剂对年龄相关性黄斑变性的影响]

[The effect of selected vitamins, minarals and antioxidants on age-related macular degeneration].

作者信息

Okręglicka Katarzyna, Skwierczyńska Żaneta, Wiśniewska Klaudia, Kozłowska Aleksandra, Jagielska Anna, Nitsch-Osuch Aneta

机构信息

Department of Social Medicine and Public Health, Medical University of Warsaw, Poland.

Student Science Group of Hygiene and Prophylaxis in Department of Social Medicine and Public Health, Medical University of Warsaw, Poland.

出版信息

Pol Merkur Lekarski. 2019 Jul 29;47(277):35-39.

Abstract

Age-related macular degeneration (AMD) is a progressively degenerative disease at the central area of the retina, which results in severe visual impairment. It is the leading cause of irreversible blindness among people aged over 65 in developed countries. Therapies that focus on prevention through optimization of modifiable risk factors such as diet and nutritional status are key approaches to reducing the burden of disease. An adequate diet, especially rich in antioxidant compounds, seems to play an important role in this case. Available scientific data suggest that vitamins A, E, C and carotenoids, in particular lutein and zeaxantine and some minerals, may play an important role in the prevention and / or delay of AMD. There are also new data on the importance of other ingredients such as flavonoids in the AMD development. In this work, based on the available data, the study reviews the relationship between the intake of selected antioxidant nutrients and age-related macular degeneration.

摘要

年龄相关性黄斑变性(AMD)是一种发生于视网膜中心区域的进行性退行性疾病,可导致严重的视力损害。它是发达国家65岁以上人群不可逆失明的主要原因。通过优化饮食和营养状况等可改变的风险因素来进行预防的疗法是减轻疾病负担的关键途径。在这种情况下,充足的饮食,尤其是富含抗氧化化合物的饮食,似乎起着重要作用。现有的科学数据表明,维生素A、E、C和类胡萝卜素,特别是叶黄素和玉米黄质以及一些矿物质,可能在预防和/或延缓AMD方面发挥重要作用。关于其他成分如黄酮类化合物在AMD发展中的重要性也有新的数据。在这项工作中,基于现有数据,该研究综述了所选抗氧化营养素的摄入与年龄相关性黄斑变性之间的关系。

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