Department of Biology, University of Western Ontario, London, ON, N6A-5B7, Canada.
Synthetic Genomics Inc., La Jolla, California, 92037, USA.
Curr Biol. 2019 Aug 5;29(15):R736-R737. doi: 10.1016/j.cub.2019.06.040.
The chlamydomonadalean green alga Haematococcus lacustris (strain UTEX 2505) has the largest chloroplast genome on record: 1352 kb with ∼90% non-coding DNA [1,2]. But what of the mitochondrial genome? Here we present sequencing, assembly, and analysis of the mitogenome that shows that it, too, is extremely expanded. What's more, the same repetitive elements have spread throughout the mitochondrial and chloroplast (or plastid) DNA (mtDNA and ptDNA, respectively), resulting in the situation whereby these two distinct organelle genomes are made up of nearly identical sequences.
湖生红球藻（UTEX 2505 株）是一种有孔虫门绿藻，其叶绿体基因组是目前已知最大的，全长 1352kb，其中非编码 DNA 约占 90%[1,2]。那么它的线粒体基因组有多大呢？本文报道了对其线粒体基因组的测序、组装和分析结果，表明其线粒体基因组同样大幅扩张。更值得注意的是，同样的重复元件散布在线粒体和叶绿体（或质体）DNA（分别为 mtDNA 和 ptDNA）中，导致这两个不同的细胞器基因组由几乎完全相同的序列组成。
