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[戊二醛对细菌放射敏感性的修饰作用]

[Modification of the radiosensitivity of bacteria by glutaraldehyde].

作者信息

Vasil'eva E I

出版信息

Radiobiologiia. 1988 Jul-Aug;28(4):524-7.

PMID:3138705
Abstract

A study was made of the combined effect of ionizing radiation and various concentrations of glutaric aldehyde (0.00125, 0.0025, 0.5, and 1 per cent) on viability of bacteria differing in a cell wall structure, radiosensitivity, and activity of DNA repair system. The combined effect of the two factors was shown to produce an effect of superadditive enhancement of bacterial cell death. The synergism was more pronounced in highly radiosensitive bacteria.

摘要

研究了电离辐射与不同浓度戊二醛(0.00125%、0.0025%、0.5%和1%)对细胞壁结构、放射敏感性及DNA修复系统活性不同的细菌生存能力的联合作用。结果表明,这两种因素的联合作用产生了细菌细胞死亡超相加增强效应。这种协同作用在高放射敏感性细菌中更为明显。

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