Rexiti Paerhati, Wutiku Minawaer, Wulamu Wuhuzi, Bai FengZhou, Cao Li
Department of Orthopaedics, The First Affiliation Hospital of Xinjiang Medical University, Urumqi, China.
Department of Sonography, Fourth Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Rev Assoc Med Bras (1992). 2019 Aug 5;65(7):946-950. doi: 10.1590/1806-9282.65.7.946.
A background of Pulmonary Hypertension (PH) indicates a progressive elevation of pulmonary vascular resistance, leading to overfilling, elevation of venous pressure, congestion in various organs, and edema in the venous system. This study aimed to investigate whether PH is a risk factor for deep vein thrombosis (DVT) of the lower extremities after hip and knee replacement surgery.
A total of 238 patients who received joint replacement of lower extremities in our department of orthopedics from January 2009 to January 2012 were examined by echocardiography and Color Doppler flow imaging (CDFI) of the lower extremities. Based on pulmonary artery pressure (PAP), the patients were divided into a normal PAP group (n=214) and PH group (n=24). All the patients were re-examined by CDFI during post-operative care.
Among the 238 patients, 18 had DVT in the lower extremities after the operation. DVT total incidence rate was 7.56% (18/238). In the PH group, 11 patients had DVT (45.83%, 11/24), but in the normal PAP group, only 7 had DVT (3.27%, 7/214). The incidence of DVT was significantly lower in the normal PAP group than in the PH group (P<0.01). In addition, there was a positive correlation between PAP and the incidence of DVT.
PH could be a high-risk factor for the occurrence of DVT in patient's lower extremities after joint replacement surgeries.
肺动脉高压（PH）背景提示肺血管阻力进行性升高，导致血容量过多、静脉压升高、各器官淤血及静脉系统水肿。本研究旨在调查PH是否为髋膝关节置换术后下肢深静脉血栓形成（DVT）的危险因素。
选取2009年1月至2012年1月在我院骨科接受下肢关节置换的238例患者，行超声心动图及下肢彩色多普勒血流成像（CDFI）检查。根据肺动脉压（PAP）将患者分为正常PAP组（n = 214）和PH组（n = 24）。所有患者在术后护理期间均接受CDFI复查。
238例患者中，术后有18例发生下肢DVT。DVT总发生率为7.56%（18/238）。PH组有11例发生DVT（45.83%，11/24），而正常PAP组仅有7例发生DVT（3.27%，7/214）。正常PAP组DVT发生率显著低于PH组（P < 0.01）。此外，PAP与DVT发生率呈正相关。
PH可能是关节置换术后患者下肢发生DVT的高危因素。
