Tosi Filippo, Stuart Marc C A, Wezenberg Sander J, Feringa Ben L
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.
Angew Chem Int Ed Engl. 2019 Oct 14;58(42):14935-14939. doi: 10.1002/anie.201908010. Epub 2019 Sep 5.
Tuning morphologies of self-assembled structures in water is a major challenge. Herein we present a salen-based amphiphile which, using complexation with distinct transition metal ions, allows to control effectively the self-assembly morphology in water, as observed by Cryo-TEM and confirmed by DLS measurements. Applying this strategy with various metal ions gives a broad spectrum of self-assembled structures starting from the same amphiphilic ligand (from cubic structures to vesicles and micelles). Thermogravimetric analysis and electric conductivity measurements reveal a key role for water coordination apparently being responsible for the distinct assembly behavior.
在水中调节自组装结构的形态是一项重大挑战。在此，我们展示了一种基于双水杨醛缩乙二胺的两亲分子，通过与不同的过渡金属离子络合，能够有效控制在水中的自组装形态，这一结果通过冷冻透射电子显微镜观察到，并经动态光散射测量得到证实。将该策略应用于各种金属离子，从相同的两亲配体出发可得到广泛的自组装结构（从立方结构到囊泡和胶束）。热重分析和电导率测量揭示了水配位的关键作用，显然它是导致不同组装行为的原因。
