Burkes Jonathan C, Anderson John T
Department of Orthopedic Surgery, Kansas University Medical Center, Kansas City, Kansas.
Department of Orthopedic Surgery, The Children's Mercy Hospital, Kansas City, Missouri.
JBJS Case Connect. 2019 Jul-Sep;9(3):e0159. doi: 10.2106/JBJS.CC.18.00159.
This report describes a 7-year-old girl with Langerhans cell histiocytosis (LCH) of the thoracic spine who developed neurological deterioration during nonsurgical management. She was treated with decompression and instrumented fusion followed by chemotherapy, recovered completely after surgery, and was doing well at 6-year follow-up.
The best treatment of LCH of the spine is not clear, but in the setting of neurologic compromise after failing conservative management, surgical decompression with adjuvant chemotherapy should be considered.
本报告描述了一名患有胸椎朗格汉斯细胞组织细胞增多症（LCH）的7岁女孩，她在非手术治疗期间出现神经功能恶化。她接受了减压和器械融合手术，随后进行化疗，术后完全康复，在6年随访时情况良好。
脊柱LCH的最佳治疗方法尚不清楚，但在保守治疗失败后出现神经功能损害的情况下，应考虑手术减压并辅以化疗。
