Azizollahi Hamid, Mehta Vaibhav P, García-López José-Antonio
Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, 91775-1436, Mashhad, Iran.
Chem Commun (Camb). 2019 Aug 22;55(69):10281-10284. doi: 10.1039/c9cc04817k.
We report two ligand-controlled cascade reactions relying on the intramolecular carbopalladation of skipped dienes. The use of a bulky monodentate phosphine ligand affords [4,5]-spirocycles via sequential double carbopalladation, however bidentate phosphines promote a remote β-C-elimination process which does not rely on the use of strained or sterically hindered substrates.
我们报道了两个依赖于跳跃二烯分子内碳钯化反应的配体控制级联反应。使用大位阻单齿膦配体通过连续的双碳钯化反应生成[4,5]-螺环化合物，然而双齿膦会促进一个远程β-C消除过程，该过程不依赖于使用张力或空间位阻较大的底物。
