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Interaction between cannabinoid and nucleotide systems as a new mechanism of signaling in retinal cell death.

作者信息

Freitas Hércules R, Reis Ricardo A M, Ventura Ana L M, França Guilherme R

机构信息

Laboratory of Neurochemistry, Institute of Biophysics Carlos Chagas Filho, Universidade Federal do Rio de Janeiro; School of Health Sciences, Centro Universitário IBMR, Rio de Janeiro, RJ, Brazil.

Laboratory of Neurochemistry, Institute of Biophysics Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

出版信息

Neural Regen Res. 2019 Dec;14(12):2093-2094. doi: 10.4103/1673-5374.262585.

DOI:10.4103/1673-5374.262585
PMID:31397346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6788250/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3804/6788250/15d90686bcab/NRR-14-2093-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3804/6788250/15d90686bcab/NRR-14-2093-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3804/6788250/15d90686bcab/NRR-14-2093-g001.jpg

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Cannabinoids Induce Cell Death and Promote P2X7 Receptor Signaling in Retinal Glial Progenitors in Culture.大麻素在培养的视网膜神经胶质前体细胞中诱导细胞死亡并促进 P2X7 受体信号转导。
Mol Neurobiol. 2019 Sep;56(9):6472-6486. doi: 10.1007/s12035-019-1537-y. Epub 2019 Mar 5.
2
Purinergic signaling in the retina: From development to disease.嘌呤能信号在视网膜中的作用:从发育到疾病。
Brain Res Bull. 2019 Sep;151:92-108. doi: 10.1016/j.brainresbull.2018.10.016. Epub 2018 Nov 17.
3
CB receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells.
CB 受体的激活会导致人 RPE 细胞中 ERK1/2 依赖的炎症反应。
Sci Rep. 2017 Nov 23;7(1):16169. doi: 10.1038/s41598-017-16524-w.
4
Neuroprotective effect of cannabinoid receptor 1 antagonist in the MNU-induced retinal degeneration model.大麻素受体 1 拮抗剂在 MNU 诱导的视网膜变性模型中的神经保护作用。
Exp Eye Res. 2018 Feb;167:145-151. doi: 10.1016/j.exer.2017.11.001. Epub 2017 Nov 7.
5
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Eur J Pharmacol. 2017 May 15;803:78-83. doi: 10.1016/j.ejphar.2017.03.018. Epub 2017 Mar 16.
6
Endogenous and Synthetic Cannabinoids as Therapeutics in Retinal Disease.内源性和合成大麻素在视网膜疾病治疗中的应用
Neural Plast. 2016;2016:8373020. doi: 10.1155/2016/8373020. Epub 2016 Jan 6.
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Inflammation and its role in age-related macular degeneration.炎症及其在年龄相关性黄斑变性中的作用。
Cell Mol Life Sci. 2016 May;73(9):1765-86. doi: 10.1007/s00018-016-2147-8. Epub 2016 Feb 6.
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