胰岛自身抗体的诞生与发展。
Birth and coming of age of islet autoantibodies.
机构信息
Technische Universität Dresden, DFG Center for Regenerative Therapies Dresden, Dresden, Germany.
Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital Carl Gustav Carus and Faculty of Medicine, TU Dresden, Dresden, Germany.
出版信息
Clin Exp Immunol. 2019 Dec;198(3):294-305. doi: 10.1111/cei.13360. Epub 2019 Sep 12.
This review takes the reader through 45 years of islet autoantibody research, from the discovery of islet-cell antibodies in 1974 to today's population-based screening for presymptomatic early-stage type 1 diabetes. The review emphasizes the current practical value of, and factors to be considered in, the measurement of islet autoantibodies.
本文带读者回顾了 45 年的胰岛自身抗体研究，从 1974 年发现胰岛细胞抗体到今天基于人群的早期 1 型糖尿病无症状期筛查。本文强调了目前测量胰岛自身抗体的实际价值和需要考虑的因素。
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