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香薰蜡烛作为增加膀胱癌风险的未被认知因素;有足够的证据引起警惕吗?

Scented Candles as an Unrecognized Factor that Increases the Risk of Bladder Cancer; Is There Enough Evidence to Raise a Red Flag?

机构信息

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.

Department of Urology Memorial Rydygier Hospital Cracow Poland.

出版信息

Cancer Prev Res (Phila). 2019 Oct;12(10):645-652. doi: 10.1158/1940-6207.CAPR-19-0093. Epub 2019 Aug 9.

DOI:10.1158/1940-6207.CAPR-19-0093
PMID:31399420
Abstract

The causes of bladder cancer are not yet fully uncovered, however the research has identified a number of factors that may increase the risk of developing this cancer. The chemical carcinogenesis of bladder cancer due to chronic exposure to aromatic hydrocarbons has been well-established. The identification of this correlation led to an improvement of safety measures in chemical industry and a gradual decrease of bladder cancer cases among workers. Nevertheless, in the majority of bladder cancer cases, the specific cause of the disease still can't be specified. It makes the question of unrecognized factors associated with bladder cancer development even more relevant. Taking under consideration known chemical carcinogenesis of bladder cancer, this minireview takes under investigation the possible link between using scented candles and a risk of bladder cancer development. Burning scented candles contain many of the substances that are associated with a bladder cancer. Furthermore the scented candles are not only very popular but also widely available on the market, with limited quality regulations and unspecified raw materials determining a spectrum of potentially dangerous substances emitted during burning.

摘要

膀胱癌的病因尚未完全阐明,但研究已经确定了一些可能增加患膀胱癌风险的因素。由于长期接触芳香烃,膀胱癌的化学致癌作用已得到充分证实。这一相关性的发现促使化工行业采取了更安全的措施,膀胱癌患者数量在工人中逐渐减少。然而,在大多数膀胱癌病例中,仍无法确定疾病的确切病因。这使得与膀胱癌发展相关的未知因素的问题更加突出。鉴于膀胱癌的已知化学致癌作用,本综述探讨了使用香薰蜡烛与膀胱癌发展风险之间可能存在的联系。香薰蜡烛的燃烧会释放出许多与膀胱癌相关的物质。此外,香薰蜡烛不仅非常受欢迎,而且在市场上也广泛供应,但质量监管有限,原材料未明确,这决定了燃烧过程中会释放出一系列潜在危险物质。

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