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肩稳定手术后的阿片类药物使用:延长使用的风险因素。

Opioid use following shoulder stabilization surgery: risk factors for prolonged use.

机构信息

Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

Division of Sports Medicine, Midwest Orthopedics at Rush, Rush University Medical Center, Chicago, IL, USA.

出版信息

J Shoulder Elbow Surg. 2019 Oct;28(10):1928-1935. doi: 10.1016/j.jse.2019.05.026. Epub 2019 Aug 7.

Abstract

HYPOTHESIS

The purpose of this study was to determine the rate of opioid use before and after shoulder stabilization surgery for instability due to recurrent dislocation and assess patient factors associated with prolonged opioid use postoperatively.

METHODS

Patients undergoing primary shoulder stabilization procedures for shoulder instability due to recurrent dislocation were accessed from the Humana administrative claims database. Patients were categorized as those who filled 1 or more opioid prescriptions within 1 month, those who filled opioid prescriptions between 1 and 3 months, and those who never filled opioid prescriptions before surgery. Rates of opioid use were evaluated preoperatively and longitudinally tracked for each group. Multiple binomial logistic regression analysis was used to identify factors associated with opioid use at 3 months and 1 year after surgery.

RESULTS

Overall, 4802 patients (45.9% opioid naive) underwent shoulder stabilization surgery for shoulder instability during the study period. Rates of opioid use significantly declined after the first postoperative month; however, at 1 year, the rate of opioid use was significantly greater in patients who filled opioid prescriptions preoperatively (13.4% vs. 1.9%, P < .0001). Filling opioid prescriptions 1 to 3 months prior to surgery was the strongest risk factor for opioid use at 1 year after surgery.

CONCLUSIONS

Patients who were prescribed opioids 1 to 3 months before surgery had the highest risk of prolonged opioid use following surgery. Obesity, tobacco use, and a preoperative diagnosis of fibromyalgia were independently associated with prolonged opioid use following surgery.

摘要

假设

本研究旨在确定因复发性脱位导致不稳定而接受肩部稳定手术前后阿片类药物使用的比率,并评估与术后长期使用阿片类药物相关的患者因素。

方法

从 Humana 行政索赔数据库中获取因复发性脱位导致肩部不稳定而接受初次肩部稳定手术的患者。将患者分为以下几组:1 个月内使用 1 种或多种阿片类药物的患者、1 至 3 个月内使用阿片类药物的患者和术前从未使用过阿片类药物的患者。评估术前和每组的纵向跟踪阿片类药物的使用情况。使用多项二项逻辑回归分析来确定与术后 3 个月和 1 年阿片类药物使用相关的因素。

结果

在研究期间,共有 4802 例(45.9%的阿片类药物未使用)患者因肩部不稳定接受肩部稳定手术。术后第一个月阿片类药物使用率显著下降;然而,1 年后,术前使用阿片类药物的患者阿片类药物使用率显著更高(13.4%比 1.9%,P<.0001)。术前 1 至 3 个月内开具阿片类药物处方是术后 1 年阿片类药物使用的最强危险因素。

结论

术前 1 至 3 个月开具阿片类药物处方的患者术后长期使用阿片类药物的风险最高。肥胖、吸烟和术前纤维肌痛诊断与术后长期使用阿片类药物独立相关。

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