青霉胺诱发的IgA缺乏症（作者译）
[D-penicillamin-induced IgA-deficiency (author's transl)].
作者信息
Götze H
出版信息
Klin Padiatr. 1979 Jul;191(4):433-5.
PMID:314018
Abstract
A 6 year old girl developed IgA-deficiency following treatment for chronic hepatitis with D-penicillamine. 4 months after discontinuation of the drug serum IgA and the number of circulating B-lymphocytes were still markedly reduced, in addition secretory IgA was diminished relative to secretory IgM. D-penicillamine should be used only if absolutely necessary and during treatment frequent monitoring of immunoglobulin levels becomes mandatory.
摘要
一名6岁女孩在接受青霉胺治疗慢性肝炎后出现IgA缺乏。停药4个月后，血清IgA和循环B淋巴细胞数量仍显著减少，此外，分泌型IgA相对于分泌型IgM减少。仅在绝对必要时才应使用青霉胺，并且在治疗期间必须频繁监测免疫球蛋白水平。
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