Department of Psychiatry Research, Dartmouth-Hitchcock, Lebanon, New Hampshire, and Department of Psychiatry, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Psychiatr Serv. 2019 Nov 1;70(11):1000-1005. doi: 10.1176/appi.ps.201800403. Epub 2019 Aug 12.
Despite the important impact of sexuality on quality of life in adults, there is a paucity of research on this topic for people with schizophrenia. This study examined predictors of sexual interest among adults with schizophrenia.
Using data from three studies with similar measures and participants with similar characteristics (N=231), the authors conducted a secondary analysis to examine the relationships among sexual interest, demographic characteristics (gender, age, living situation, and marital status), and clinical factors (sexual self-efficacy, symptom severity, and medications). Sexual interest was measured by using one item from the Scale to Assess Negative Symptoms. Binomial logistic regressions were conducted to explore factors most associated with level of sexual interest.
Separately, cardiovascular medications, gender, age, sexual self-efficacy, and negative symptoms were associated with sexual interest. In a logistic regression model that included all of these factors, only sexual self-efficacy and gender were significantly associated with sexual interest. Higher levels of sexual self-efficacy were associated with lower levels of impairment in sexual interest (odds ratio [OR]=0.98, 95% confidence interval [CI]=0.98-0.99, p<0.001), and males were less likely than females to have impaired sexual interest (OR=0.38, 95% CI=0.20-0.73, p=0.004).
The strength of the relationship between sexual self-efficacy and sexual interest warrants development of interventions to address sexuality among people with serious mental illness, at least for those who are interested in developing or maintaining intimate relationships. An intervention that teaches skills needed to successfully pursue and navigate intimate relationships could positively influence overall quality of life for many.
尽管性行为对成年人的生活质量有重要影响，但针对精神分裂症患者的这一主题的研究却很少。本研究调查了精神分裂症成年人性兴趣的预测因素。
使用来自三项具有相似措施和参与者特征的研究的数据（N=231），作者进行了二次分析，以检验性兴趣与人口统计学特征（性别、年龄、生活状况和婚姻状况）和临床因素（性自我效能、症状严重程度和药物）之间的关系。性兴趣通过使用负面症状量表中的一个项目来衡量。采用二项逻辑回归探讨与性兴趣水平最相关的因素。
心血管药物、性别、年龄、性自我效能和负面症状分别与性兴趣相关。在包括所有这些因素的逻辑回归模型中，只有性自我效能和性别与性兴趣显著相关。较高的性自我效能与性兴趣受损程度较低相关（比值比[OR]=0.98，95%置信区间[CI]=0.98-0.99，p<0.001），男性比女性更不可能出现性兴趣受损（OR=0.38，95% CI=0.20-0.73，p=0.004）。
性自我效能与性兴趣之间的关系强度表明，至少对于那些有兴趣发展或维持亲密关系的人，需要制定干预措施来解决严重精神疾病患者的性问题。教授成功追求和驾驭亲密关系所需技能的干预措施可能会对许多人的整体生活质量产生积极影响。
