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阿洪病,喀麦隆一名女性身上的罕见致残性皮肤病:病例报告

Ainhum, a rare mutilating dermatological disease in a female Cameroonian: a case report.

作者信息

Tchouakam Diego Nitcheu, Tochie Joel Noutakdie, Guifo Marc Leroy, Choukem Simeon Pierre

机构信息

Health and Human Development (2HD) Research Network, Douala, Cameroon.

Bogo District Hospital, Bogo, Cameroon.

出版信息

BMC Dermatol. 2019 Aug 12;19(1):12. doi: 10.1186/s12895-019-0092-6.

DOI:10.1186/s12895-019-0092-6
PMID:31401977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6689862/
Abstract

BACKGROUND

Ainhum is an idiopathic dermatological disease characterized by a progressive constricting ring usually on the fifth toe, which may lead to spontaneous auto-amputation of the affected toe. Timely diagnosis and treatment are the key elements to avert amputations with resultant mutilating deformities, permanent handicaps and psychological sequelae. Though common in African descents, this pathology has not been described in the Cameroonian literature. Herein, we report the case of an adult Cameroonian woman presenting with ainhum.

CASE PRESENTATION

A 54-year old Cameroonian was admitted to our primary healthcare centre with a 6-month history of a painful constriction band developing at the base of her right fifth toe. Her past history was uneventful. Based on the absence of trauma and spontaneous onset of the condition, the diagnosis of ainhum was most suggestive. She was managed surgically by excision of the band, disarticulated at right fifth metatarsophalangeal joint and skin closure. Her post-operative course after 1 year was uneventful.

CONCLUSION

Here we presented a case of ainhum, a rare dermatological disease with few reports. In view of the serious complications of ainhum such as mutilating deformities with permanent physical disabilities and psychological trauma, we draw clinicians' attention, especially wound care specialists to this rare but potentially handicapping disease, for timely diagnosis and management.

摘要

背景

阿洪病是一种特发性皮肤病,其特征为通常在第五趾出现进行性缩窄环,这可能导致患趾自发自截。及时诊断和治疗是避免截肢以及由此产生的致残畸形、永久性残疾和心理后遗症的关键因素。尽管在非洲裔人群中常见,但喀麦隆文献中尚未描述过这种病症。在此,我们报告一例患有阿洪病的喀麦隆成年女性病例。

病例介绍

一名54岁的喀麦隆女性因右第五趾根部出现疼痛性缩窄带6个月而入住我们的基层医疗中心。她既往史无异常。基于无创伤且病情自发出现,阿洪病的诊断最具提示性。她接受了手术治疗,切除缩窄带,在右第五跖趾关节处离断并缝合皮肤。术后1年她的病程平稳。

结论

我们在此呈现了一例阿洪病病例,这是一种罕见且报道较少的皮肤病。鉴于阿洪病的严重并发症,如致残畸形、永久性身体残疾和心理创伤,我们提请临床医生,尤其是伤口护理专家关注这种罕见但可能导致残疾的疾病,以便及时诊断和处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/6689862/3c44a215c9b8/12895_2019_92_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/6689862/7970c120b76c/12895_2019_92_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/6689862/3c44a215c9b8/12895_2019_92_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/6689862/7970c120b76c/12895_2019_92_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/6689862/3c44a215c9b8/12895_2019_92_Fig2_HTML.jpg

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本文引用的文献

1
Ainhum - A Rare Case Report.自发性断趾症——一例罕见病例报告
J Clin Diagn Res. 2016 Apr;10(4):PD17-8. doi: 10.7860/JCDR/2016/17556.7648. Epub 2016 Apr 1.
2
Ainhum: A Spot Diagnosis.阿洪病:一种现场诊断
Indian J Surg. 2015 Dec;77(Suppl 3):1411-2. doi: 10.1007/s12262-014-1160-0. Epub 2014 Aug 28.
3
Familial ainhum: a case report of multiple toe involvement in a father and son, staging of ainhum with insight into different types of constricting bands.家族性自发性断趾症:父子均有多趾受累的病例报告,自发性断趾症的分期及对不同类型缩窄带的深入分析
甲沟炎门诊手术治疗后发生手术部位感染导致坏疽和截肢:一例病例报告。
Patient Saf Surg. 2019 Dec 16;13:44. doi: 10.1186/s13037-019-0225-1. eCollection 2019.
Indian J Dermatol. 2015 Jan-Feb;60(1):106. doi: 10.4103/0019-5154.147879.
4
[Ainhum and "African acral keratoderma": three cases].[阿洪病与“非洲肢端角化病”:三例]
Ann Dermatol Venereol. 2015 Mar;142(3):170-5. doi: 10.1016/j.annder.2014.11.013. Epub 2015 Jan 23.
5
Ainhum (dactylolysis spontanea): a case with hands and feet involvement.指骨离断症(自发性断指):累及手和足的病例。
J Clin Rheumatol. 2013 Aug;19(5):277-9. doi: 10.1097/RHU.0b013e31829d517f.
6
Palmoplantar keratodermas in black patients (Fitzpatrick skin phototype V-VI) of African descent: a multicentre comparative and descriptive series.非洲裔黑人患者(菲茨帕特里克皮肤光类型V - VI)的掌跖角化病:一项多中心比较性和描述性研究系列
Br J Dermatol. 2011 Jul;165(1):219-21. doi: 10.1111/j.1365-2133.2011.10325.x.
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Ainhum; a clinical summary of forty-five cases on the Isthmus of Panama.阿洪病;巴拿马地峡45例临床总结。
Trans R Soc Trop Med Hyg. 1945;39(4):331-4. doi: 10.1016/0035-9203(46)90045-4.
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Palmoplantar keratoderma, pseudo-ainhum, and universal atrichia: A new patient and review of the palmoplantar keratoderma-congenital alopecia syndrome.掌跖角化病、假性并指畸形和全身性无毛发:一位新患者及掌跖角化病-先天性秃发综合征的回顾。
Am J Med Genet A. 2010 Aug;152A(8):2043-7. doi: 10.1002/ajmg.a.33490.
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