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述情障碍、韧性、躯体感觉及其与首发重性抑郁障碍未用药患者自杀意念的关系:“真实世界”日常临床实践中的探索性研究。

Alexithymia, resilience, somatic sensations and their relationships with suicide ideation in drug naïve patients with first-episode major depression: An exploratory study in the "real world" everyday clinical practice.

机构信息

NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital "G. Mazzini," ASL 4, Teramo, Italy.

Department of Neurosciences and Imaging, Chair of Psychiatry, University "G. D'Annunzio", Chieti, Italy.

出版信息

Early Interv Psychiatry. 2020 Jun;14(3):336-342. doi: 10.1111/eip.12863. Epub 2019 Aug 11.

Abstract

AIM

The present study is aimed at revaluating alexithymia, somatic sensations, resilience and their relationships with suicide ideation in drug naïve adult outpatients suffering from first episode major depression (MD).

METHODS

Data of 103 adult outpatients (49 men, 56 women) with a diagnostic and statistical manual of mental disorders, 4th edition, text revision (DSM-IV-TR) diagnosis of MD were analysed. Alexithymia was measured using the 20-item Toronto Alexithymia Scale (TAS-20) and resilience with the 25 items Connor-Davidson Resilience Scale (CD-RISC) whereas depression was evaluated using the 17-item Hamilton Depression Rating Scale, somatic sensations with the Body Sensations Questionnaire and suicide ideation with Scale of Suicide Ideation (SSI).

RESULTS

Gender comparisons between all demographic and clinical variables showed no significant differences in all variables. Subjects who were found positive for alexithymia showed higher scores on all clinical variables controlling for age, gender and duration of the current episode. In a linear regression model, lower scores on CD-RISC and Difficulty in Identifying Feelings dimension of TAS-20 were significantly predictive of higher scores on SSI.

CONCLUSIONS

Alexithymia and low resilience were significant predictors of increased suicide ideation in a first MD episode. However, study limitations must be considered and future research needs are being discussed.

摘要

目的

本研究旨在重新评估述情障碍、躯体感觉、韧性及其与首次发作的单相重性抑郁障碍(MD)成年门诊患者自杀意念的关系。

方法

分析了 103 名成年门诊患者(49 名男性,56 名女性)的诊断和统计手册,第 4 版,文本修订版(DSM-IV-TR)MD 的诊断数据。使用 20 项多伦多述情障碍量表(TAS-20)和 25 项康纳-戴维森韧性量表(CD-RISC)测量述情障碍,使用 17 项汉密尔顿抑郁评定量表测量抑郁,使用身体感觉问卷测量躯体感觉,使用自杀意念量表(SSI)测量自杀意念。

结果

对所有人口统计学和临床变量进行性别比较,在所有变量中均无显著差异。在控制年龄、性别和当前发作持续时间后,发现存在述情障碍的患者在所有临床变量上的得分均较高。在线性回归模型中,CD-RISC 评分较低和 TAS-20 的识别困难维度得分较低与 SSI 得分较高显著相关。

结论

在首次 MD 发作中,述情障碍和低韧性是自杀意念增加的显著预测因素。然而,必须考虑到研究的局限性,并且正在讨论未来的研究需求。

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