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1
Continuing outbreak of hepatitis A linked with intravenous drug abuse in Multnomah County.与Multnomah县静脉注射吸毒相关的甲型肝炎持续爆发。
Public Health Rep. 1988 Sep-Oct;103(5):452-9.
2
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3
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Clin Pediatr (Phila). 1971 Apr;10(4):191-3. doi: 10.1177/000992287101000403.
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Hepatitis A outbreaks among illicit drug users and their contacts in Queensland, 1997.
Med J Aust. 1999 Jun 21;170(12):584-7. doi: 10.5694/j.1326-5377.1999.tb127904.x.
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The role of child care in a community-wide outbreak of hepatitis A.儿童保育在甲型肝炎社区范围内暴发中的作用。
Pediatrics. 2001 Nov;108(5):E78. doi: 10.1542/peds.108.5.e78.
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Epidemiology of endemic viral hepatitis in an urban area of India: a retrospective community study in Alwar.印度某城市地区地方性病毒性肝炎的流行病学:阿尔瓦尔的一项回顾性社区研究
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Increased occurrence of hepatitis A with cyclic outbreaks among drug addicts in a Swedish community.瑞典某社区吸毒者中甲型肝炎发病率上升且呈周期性暴发。
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Eur J Gastroenterol Hepatol. 2003 Aug;15(8):901-6. doi: 10.1097/00042737-200308000-00011.
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引用本文的文献

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Economic impact of a hepatitis A epidemic in a mid-sized urban community: the case of Spokane, Washington.甲型肝炎疫情对一个中型城市社区的经济影响:以华盛顿州斯波坎市为例。
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Improving access to primary health care for chronic drug users: an innovative systemic intervention for providers.改善慢性吸毒者获得初级卫生保健的机会:为提供者提供的一种创新性系统干预措施。
J Behav Health Serv Res. 2002 Nov;29(4):445-57. doi: 10.1007/BF02287350.
3
Illicit drug use and emergency room utilization.非法药物使用与急诊室利用情况。
Health Serv Res. 2000 Apr;35(1 Pt 1):153-69.
4
Identifying target groups for a potential vaccination program during a hepatitis A communitywide outbreak.在甲型肝炎社区范围内爆发期间确定潜在疫苗接种计划的目标群体。
Am J Public Health. 1999 Jun;89(6):918-21. doi: 10.2105/ajph.89.6.918.
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Factors in hepatitis A transmission.甲型肝炎传播的因素。
Am J Public Health. 1989 Nov;79(11):1571. doi: 10.2105/ajph.79.11.1571.

本文引用的文献

1
Acute hepatitis A, B and non-A, non-B in a Swedish community studied over a ten-year period.对瑞典一个社区进行了为期十年的研究,观察急性甲型、乙型及非甲非乙型肝炎。
Scand J Infect Dis. 1982;14(4):253-9. doi: 10.3109/inf.1982.14.issue-4.02.
2
Viral hepatitis among parenteral drug addicts attending a Danish addiction clinic.
Scand J Infect Dis. 1983;15(2):139-43. doi: 10.3109/inf.1983.15.issue-2.02.
3
Epidemiology of drug abuse: an overview.
Science. 1986 Nov 21;234(4779):970-4. doi: 10.1126/science.3490691.
4
Trends in intravenous drug abuse as reflected in national hepatitis reporting.国家肝炎报告所反映的静脉注射药物滥用趋势。
Am J Public Health. 1976 Sep;66(9):872-7. doi: 10.2105/ajph.66.9.872.
5
The epidemiological pattern of hepatitis A, B, and non-A, non-B in Sweden.瑞典甲型、乙型及非甲非乙型肝炎的流行病学模式。
Scand J Gastroenterol. 1978;13(7):873-7. doi: 10.3109/00365527809182206.

与Multnomah县静脉注射吸毒相关的甲型肝炎持续爆发。

Continuing outbreak of hepatitis A linked with intravenous drug abuse in Multnomah County.

作者信息

Schade C P, Komorwska D

机构信息

Department of Human Services, Multnomah County, OR.

出版信息

Public Health Rep. 1988 Sep-Oct;103(5):452-9.

PMID:3140269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1478131/
Abstract

A communitywide outbreak of hepatitis A occurred in Portland, OR, from 1983 through 1986. At the peak of the outbreak, the age- and sex-specific annual incidence rate approached 400 cases per 100,000 population among men ages 25 to 34, the highest risk group. The community incidence rate was nearly 10 times the relevant national incidence rate. A review of the records concerning cases of hepatitis A reported in the last 6 months of 1985 revealed that about half the number of young adults whose cases were investigated during that time reported a history of intravenous (IV) drug use--a proportion about 50 times greater than expected among persons in that age range. A simultaneous epidemic of overdose deaths from heroin and a concomitant increase in hepatitis B incidence rates led to the suspicion that this was a drug-abuse-associated epidemic of hepatitis among new IV drug users. Control of this outbreak was difficult because the population most at risk was distrustful of public health officials. Increased surveillance in food service establishments and schools might have prevented outbreaks from a common source in the general population; however, an increase of sporadic cases in the nondrug-using population clearly occurred.

摘要

1983年至1986年期间,俄勒冈州波特兰市爆发了甲型肝炎社区疫情。在疫情高峰期,25至34岁男性这一最高风险群体中,按年龄和性别划分的年发病率接近每10万人400例。社区发病率几乎是全国相关发病率的10倍。对1985年最后6个月报告的甲型肝炎病例记录进行审查发现,在此期间接受调查的年轻成年人中,约有一半报告有静脉注射吸毒史,这一比例比该年龄范围内人群的预期比例高出约50倍。同时发生的海洛因过量致死疫情以及乙型肝炎发病率的相应上升,引发了人们对这是新的静脉注射吸毒者中与药物滥用相关的甲型肝炎疫情的怀疑。此次疫情的控制难度很大,因为风险最高的人群不信任公共卫生官员。加强对食品服务场所和学校的监测或许可以预防普通人群中共同来源引发的疫情;然而,非吸毒人群中散发病例明显增加。