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关于婴儿内镜下第三脑室造瘘术的知识匮乏。

The Scanty Knowledge of Endoscopic Third Ventriculostomy in Infants.

作者信息

Alqroom Rami, Al-Khawaldeh Maher, Makhamreh Basel, Sha'ban Firas, Haddad Feras, Abu-Nowar Hussam, Younes Basel, Khasawneh Nidal, Shurbaji Amer Al

机构信息

Neurosurgery Department, King Hussein Medical Center, Royal Medical Services, Amman, Jordan.

Interventional Interventional Radiology-neuroradiology Department, King Hussein Medical Center, Royal medical services, Amman, Jordan.

出版信息

Med Arch. 2019 Jun;73(3):187-190. doi: 10.5455/medarh.2019.73.187-190.

DOI:10.5455/medarh.2019.73.187-190
PMID:31402803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6643332/
Abstract

INTRODUCTION

Hydrocephalus (HCP) remains one of the commonest pathologies treated in developing countries. Endoscopic third ventriculostomy (ETV) has become the alternative to shunt-divergen procedures in the treatment of many pathologies of the cerebral fluid in the brain. Age has been considered a limitation to perform the procedure, we started to perform ETV In younger patients earlier than many other units. Objectives: In this study, we demonstrate the overall efficacy of ETV in infants younger than 1-year of age and to subsequently report the outcome of this procedure.

METHODS

From 2000 till 2016 we have performed a total of 386 cases of ETV of all ages. 71-cases were infants (below 1-year of age). Our study was undertaken to evaluate these cases. Patients were divided into two subgroups according to the cause of hydrocephalus; obstructive HCP, communicating HCP.

RESULTS

Mean time for follow up was 52 months. Mean age at surgery was 137days (7- 351days). The population included 31-females and 40-males, while10 infants were premature. Success rates were; 91.6%, 63.6% correspond to each sub-group with an overall success rate of 73.24%.

CONCLUSION

ETV in infants is feasible, technically more demanding. Success rate justifies the procedure to be performed in such age group of patients. ETV can be used, attentively, in cases of hydrocephalus associated with MMC, morbidity and mortality does not differ from the general population.

摘要

引言

脑积水(HCP)仍是发展中国家最常见的需治疗的病症之一。在治疗许多脑内脑脊液病症方面,内镜下第三脑室造瘘术(ETV)已成为分流术的替代方法。年龄曾被视为实施该手术的限制因素,我们比许多其他科室更早开始在较年轻患者中进行ETV。目的:在本研究中,我们展示ETV在1岁以下婴儿中的总体疗效,并随后报告该手术的结果。

方法

从2000年到2016年,我们共进行了386例各年龄段的ETV手术。其中71例为婴儿(1岁以下)。我们开展本研究以评估这些病例。根据脑积水病因将患者分为两个亚组;梗阻性脑积水、交通性脑积水。

结果

平均随访时间为52个月。手术时的平均年龄为137天(7 - 351天)。研究人群包括31名女性和40名男性,其中10名婴儿为早产儿。成功率分别为;91.6%,63.6%,每个亚组的总体成功率为73.24%。

结论

婴儿ETV手术是可行的,但技术要求更高。成功率证明了在该年龄组患者中进行该手术的合理性。ETV可谨慎用于与脊髓脊膜膨出相关的脑积水病例,其发病率和死亡率与一般人群无异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/19815b4e64f2/medarch-73-187-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/8bca1e8fbddd/medarch-73-187-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/108026c4238b/medarch-73-187-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/fdaef36759d4/medarch-73-187-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/19815b4e64f2/medarch-73-187-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/8bca1e8fbddd/medarch-73-187-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/108026c4238b/medarch-73-187-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/fdaef36759d4/medarch-73-187-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef2/6643332/19815b4e64f2/medarch-73-187-g004.jpg

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本文引用的文献

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Global surgery for pediatric hydrocephalus in the developing world: a review of the history, challenges, and future directions.发展中世界小儿脑积水的全球外科治疗:历史、挑战及未来方向综述
Neurosurg Focus. 2016 Nov;41(5):E11. doi: 10.3171/2016.7.FOCUS16273.
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International Infant Hydrocephalus Study: initial results of a prospective, multicenter comparison of endoscopic third ventriculostomy (ETV) and shunt for infant hydrocephalus.
国际婴儿脑积水研究:内镜下第三脑室造瘘术(ETV)与婴儿脑积水分流术前瞻性多中心比较的初步结果
Childs Nerv Syst. 2016 Jun;32(6):1039-48. doi: 10.1007/s00381-016-3095-1. Epub 2016 Apr 23.
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Endoscopic Third Ventriculostomy in Children with Myelomeningocele: A Case Series.
Pediatr Neurosurg. 2015;50(3):113-8. doi: 10.1159/000381747. Epub 2015 May 27.
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Assessment of third ventriculostomy patency with the 3D-SPACE technique: a preliminary multicenter research study.使用3D-SPACE技术评估第三脑室造瘘术的通畅性:一项初步的多中心研究。
J Neurosurg. 2015 Jun;122(6):1347-55. doi: 10.3171/2014.10.JNS14298. Epub 2015 Apr 10.
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