Mie Takafumi, Ohta Takashi, Iwamoto Takayuki, Mizumoto Rui, Arimoto Yuki, Toda Mayura, Shimizu Satoshi, Yamaguchi Shinjiro, Ito Yoshiki, Hagiwara Hideki
Department of Gastroenterology, Kansai Rosai Hospital.
Department of Clinical Oncology, Kansai Rosai Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2019;116(8):654-659. doi: 10.11405/nisshoshi.116.654.
A 42-year-old female developed type 1 diabetes mellitus at the age of 16 years and received insulin therapy. Esophagogastroduodenoscopy revealed an atrophic change localized in the gastric body and a small, protruding gastric lesion. Biopsy revealed that this lesion was gastric neuroendocrine tumor. Hence, the patient underwent en bloc resection by endoscopic submucosal resection with a ligation device. As the patient presented both autoimmune gastritis and type 1 diabetes mellitus, she was diagnosed with type 4 autoimmune polyendocrine syndrome. We report this case considering that only few cases of gastric neuroendocrine tumor with autoimmune gastritis (type A gastritis) complicated with autoimmune polyendocrine syndrome have been reported till date.