Oshima Tadayuki, Okugawa Takuya, Hori Kazutoshi, Kim Yongmin, Tanaka Junji, Watari Jiro, Miwa Hiroto
Division of Upper Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Japan.
Intern Med. 2012;51(10):1211-3. doi: 10.2169/internalmedicine.51.7077. Epub 2012 May 15.
A 41-year-old woman was referred with epigastric discomfort. She had a 20-year history of SLE. Esophagogastroduodenoscopy (EGD) examination showed severe atrophic gastritis in the stomach and a protruding lesion was detected. Histological examination showed a carcinoid tumor with cytoplasmic staining with chromogranin-A. Using an endoscopic submucosal dissection (ESD) technique, en bloc resection of the tumor was performed. No recurrence has been found for 3 years after the treatment. Type I gastric carcinoid can occur at an earlier age with AIG and autoimmune diseases such as systemic lupus erythematosus (SLE). This is the first report of gastric carcinoid that was treated by ESD.
一名41岁女性因上腹部不适前来就诊。她有20年的系统性红斑狼疮(SLE)病史。食管胃十二指肠镜检查(EGD)显示胃有严重萎缩性胃炎,并发现一个突出病变。组织学检查显示为嗜铬粒蛋白A胞质染色的类癌肿瘤。采用内镜黏膜下剥离术(ESD)技术对肿瘤进行了整块切除。治疗后3年未发现复发。I型胃类癌可在患有自身免疫性胃炎(AIG)和自身免疫性疾病(如系统性红斑狼疮(SLE))的患者中更早发生。这是首例经ESD治疗的胃类癌报告。