Popova Gorica, Boskovska Katerina, Arnaudova-Danevska Ivana, Smilevska-Spasova Olga, Jakovska Tatjana
Department of Clinical Microbiology, Institute for Respiratory Diseases in Children, Skopje, Republic of Macedonia.
Pediatric Department, Institute for Respiratory Diseases in Children, Skopje, Republic of Macedonia.
Open Access Maced J Med Sci. 2019 Jun 30;7(12):1926-1930. doi: 10.3889/oamjms.2019.551.
The clinical relevance of specimens from the lower airways is often debatable. However, they are most commonly examined for diagnosing lower respiratory tract infections (LRTIs).
This study aimed to determine the diagnostic value of sputum quality assessment about sputum culture for diagnosing LRTIs in children.
In six months, a total of 1485 sputum samples were quality assessed by using Bartlett's grading system. All samples, regardless of their quality, were cultured, identified, and antimicrobial susceptibility testing was performed by Kirby-Bauer disc-diffusion method.
Among the acceptable category, defined by Bartlett's grading system, 132 (63.2%) samples showed culture positivity of which 48 (36.4%) was most commonly isolated, followed by 22 (16.7%) and 21 (15.9%). Among the non-acceptable category, 185 (14.5%) samples were culture positive of which most commonly isolated were , and with 64 (34.6%), 54 (29.2%) and 28 (15.1%), respectively.
Sputum quality assessment is a useful tool for distinguishing the true respiratory pathogens from possible colonising flora for which antibiotic treatment should not be highly considered.
来自下呼吸道的标本的临床相关性常常存在争议。然而，它们最常用于诊断下呼吸道感染（LRTIs）。
本研究旨在确定痰液质量评估对儿童痰液培养诊断LRTIs的诊断价值。
在六个月内，使用Bartlett分级系统对总共1485份痰液样本进行质量评估。所有样本，无论质量如何，均进行培养、鉴定，并采用 Kirby-Bauer 纸片扩散法进行药敏试验。
在Bartlett分级系统定义的可接受类别中，132份（63.2%）样本显示培养阳性，其中 48份（36.4%）最常分离出，其次是22份（16.7%）和21份（15.9%）。在不可接受类别中，185份（14.5%）样本培养阳性，其中最常分离出的是 、 和 ，分别为64份（34.6%）、54份（29.2%）和28份（15.1%）。
痰液质量评估是一种有用的工具，可用于区分真正的呼吸道病原体与可能的定植菌群，对于后者不应过度考虑使用抗生素治疗。
