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慢性疼痛的成年人中,大麻使用问题、情绪调节障碍和心理健康问题之间存在关联吗?

Is there a relationship between cannabis use problems, emotion dysregulation, and mental health problems among adults with chronic pain?

作者信息

Orr Michael F, Rogers Andrew H, Shepherd Justin M, Buckner Julia D, Ditre Joseph W, Bakhshaie Jafar, Zvolensky Michael J

机构信息

Department of Psychology, University of Houston , Houston, TX, USA.

Department of Psychology, Louisiana State University , Baton Rouge, LA, USA.

出版信息

Psychol Health Med. 2020 Jul;25(6):742-755. doi: 10.1080/13548506.2019.1653485. Epub 2019 Aug 13.

Abstract

Cannabis is often used to manage pain among persons who suffer from chronic pain. Yet, despite much literature suggesting cannabis use problems are associated with mental health problems, little work has examined mechanisms of this relationship among a chronic pain population. Chronic pain is also associated with emotion dysregulation. Individuals with chronic pain who experience cannabis use problems may have less capacity to regulate negative emotions, which could relate to greater anxiety, depression, and suicidal ideation. Thus, the current study explored whether emotion dysregulation explained, in part, the relation between cannabis use problems and anxiety, depression, and suicidal ideation among adults with chronic pain. Participants were 431 opioid-using adults with current moderate to severe chronic pain, 176 were current cannabis users, of which 30.20% reported cannabis use problems. Results indicated a significant indirect relationship between cannabis use problems and anxiety [95% CI (.03, .05)], depression [95% CI (.03, .06)], and suicidal ideation [95% CI (.01, .01)] via emotion dysregulation. Tests of specificity suggested potential for a bi-directional effect for suicidal ideation (.001). Initial findings suggest that emotion dysregulation may be an important mechanism in the relationship between cannabis use problems and mental health among adults with chronic pain.

摘要

大麻常用于帮助患有慢性疼痛的人缓解疼痛。然而,尽管有大量文献表明大麻使用问题与心理健康问题有关,但很少有研究探讨慢性疼痛人群中这种关系的机制。慢性疼痛也与情绪调节障碍有关。有大麻使用问题的慢性疼痛患者调节负面情绪的能力可能较低,这可能与更高的焦虑、抑郁和自杀意念有关。因此,本研究探讨了情绪调节障碍是否部分解释了慢性疼痛成年人中大麻使用问题与焦虑、抑郁和自杀意念之间的关系。研究参与者为431名正在使用阿片类药物、患有中度至重度慢性疼痛的成年人,其中176人目前使用大麻,30.20%的人报告有大麻使用问题。结果表明,通过情绪调节障碍,大麻使用问题与焦虑[95%可信区间(.03,.05)]、抑郁[95%可信区间(.03,.06)]和自杀意念[95%可信区间(.01,.01)]之间存在显著的间接关系。特异性检验表明自杀意念存在双向效应的可能性(.001)。初步研究结果表明,情绪调节障碍可能是慢性疼痛成年人中大麻使用问题与心理健康之间关系的一个重要机制。

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