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Ceftriaxone Dosing in a Critically Ill Patient With Hypoalbuminemia During Continuous Venous Hemofiltration: Emphasis on Unbound Pharmacokinetics.

作者信息

Ebisch Renée M F, Meenks Sjoerd D, Foudraine Norbert, Janssen Paddy K C, le Noble Jos L M L

机构信息

Department of Intensive Care, VieCuri Medical Center Venlo, Venlo, the Netherlands.

Department of Hospital Pharmacy, VieCuri Medical Center Venlo, Venlo, the Netherlands.

出版信息

J Clin Pharmacol. 2020 Jan;60(1):140-142. doi: 10.1002/jcph.1503. Epub 2019 Aug 13.

DOI:10.1002/jcph.1503
PMID:31407809
Abstract
摘要

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Once-daily 1 g ceftriaxone optimizes exposure in patients with septic shock and hypoalbuminemia receiving continuous veno-venous hemodiafiltration.
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