Murakami T, Yamamoto C, Ohtsuka A, Kikuta A, Taguchi T
Department of Anatomy, Okayama University School of Medicine, Japan.
Arch Histol Cytol. 1988 Jul;51(3):263-70. doi: 10.1679/aohc.51.263.
A well developed extra-adrenal cortical body with an axis of 200-700 micron was found in eighteen of thirty adult male Wistar rats under a stereomicroscope. All eighteen bodies were located between the kidneys. Blood vascular beds of sixteen of the eighteen bodies were reproduced with a methacrylate casting medium and observed with a scanning electron microscope. The extra-adrenal cortical body was found to contain remarkably numerous capillaries which anastomosed with each other to form a conglomerated network; it received one afferent vessel and issued one to three (usually, one) efferent vessels. The blood capillaries were of sinusoidal and uniform calibers, and resembled those of the adrenal cortex. The network with an axis of 300-700 micron possessed a typical, deep efferent rootlet which corresponds to the central vein of the adrenal gland. Histological examination of the two bodies treated with Orth's or Helley's fixative confirmed that they consisted of non-chromaffin cells similar to those of the adrenal cortex. These findings suggest that in the rat, the extra-adrenal cortical bodies persist throughout life, actively producing cortical hormones.
在立体显微镜下，于30只成年雄性Wistar大鼠中的18只发现了一个发育良好的肾上腺外皮质体，其长轴为200 - 700微米。所有18个皮质体均位于两肾之间。其中18个皮质体中的16个的血管床用甲基丙烯酸酯铸型介质进行了复制，并通过扫描电子显微镜进行观察。发现肾上腺外皮质体含有大量相互吻合形成密集网络的毛细血管；它有一条输入血管，并发出一至三条（通常为一条）输出血管。血毛细血管呈窦状且口径均匀，与肾上腺皮质的毛细血管相似。长轴为300 - 700微米的网络有一条典型的深部输出小根，相当于肾上腺的中央静脉。用奥氏或赫利氏固定液处理的两个皮质体的组织学检查证实，它们由与肾上腺皮质相似的非嗜铬细胞组成。这些发现表明，在大鼠中，肾上腺外皮质体终生存在，能活跃地产生皮质激素。
