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重症监护病房中的产超广谱β-内酰胺酶肠杆菌科细菌(ESBLE):与患者 ESBLE 定植压力密切相关,但与同一菌种无关。

Extended-spectrum β-lactamase Enterobacteriaceae (ESBLE) in intensive care units: strong correlation with the ESBLE colonization pressure in patients but not same species.

机构信息

Laboratoire de bactériologie, Centre Hospitalier Universitaire, Angers, France.

Unité de prévention et de lutte contre les infections nosocomiales, Centre Hospitalier Universitaire, Angers, France.

出版信息

J Hosp Infect. 2020 Jan;104(1):53-56. doi: 10.1016/j.jhin.2019.08.007. Epub 2019 Aug 10.

DOI:10.1016/j.jhin.2019.08.007
PMID:31408692
Abstract

Sink drains of six intensive care units (ICUs) were sampled for screening contamination with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLE). A high prevalence (59.4%) of sink drain contamination was observed. Analysing the data by ICU, the ratio 'number of ESBLE species isolated in sink drains/total number of sink drains sampled' was highly correlated (Spearman coefficient: 0.87; P = 0.02) with the ratio 'number of hospitalization days for patients with ESBLE carriage identified within the preceding year/total number of hospitalization days within the preceding year'. Concurrently, the distribution of ESBLE species differed significantly between patients and sink drains.

摘要

对 6 个重症监护病房(ICU)的水槽排水管进行采样,以筛查是否存在产超广谱β-内酰胺酶的肠杆菌科(ESBLE)污染。观察到水槽排水管污染的高患病率(59.4%)。通过 ICU 对数据进行分析,“水槽排水管中分离出的 ESBLE 种类数/采样的水槽排水管总数”的比值与“前一年中携带 ESBLE 的患者的住院天数/前一年的总住院天数”的比值呈高度相关(Spearman 系数:0.87;P = 0.02)。同时,ESBLE 种类在患者和水槽排水管之间的分布差异显著。

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