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帕金森综合征社区居民的住院情况受哪些因素影响?

What Predicts Hospital Admissions in Community-Dwelling People With Parkinsonism?

作者信息

Sebastian Roshan, Gray William K, Foley Aishling, Trendall Lydia, Oh Doori, Hand Annette, Dodds Steve, McClenaghan Elliot, Santos Vasco Dos, Oates Lloyd L, Fisher James, Walker Richard W

机构信息

Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, United Kingdom.

The Medical School, Newcastle University, Newcastle-upon-Tyne, United Kingdom.

出版信息

J Geriatr Psychiatry Neurol. 2020 Mar;33(2):103-108. doi: 10.1177/0891988719868309. Epub 2019 Aug 13.

Abstract

OBJECTIVES

Previous studies have looked at the reasons for hospital admission in people with parkinsonism (PwP), yet few have looked at factors that precipitate admission.

METHODS

People with parkinsonism with a diagnosis of idiopathic Parkinson disease of Hoehn and Yahr stage III-V and those with Parkinson plus syndromes were assessed for motor and nonmotor symptoms, quality of life, and functional performance. Logistic regression was used to investigate predictors of hospital admission over the subsequent 2 years.

RESULTS

Overall, 162 patients consented to be part of the study. Seventy-one PwP (43.8%) had at least 1 hospital admission, and 17 (10.5%) patients had 3 or more admissions to hospital. Poorer cognition, more nonmotor symptoms, poorer quality of life, slower timed-up-and-go test scores, and abnormal swallow predicted a subsequent hospital admission.

DISCUSSION

Our study emphasizes the importance of nonmotor symptoms in predicting admission. A cost-benefit analysis of early intervention to prevent admission should be considered.

摘要

目的

以往研究探讨了帕金森症患者(PwP)入院的原因,但很少有研究关注促使入院的因素。

方法

对诊断为Hoehn-Yahr III-V期特发性帕金森病的帕金森症患者以及帕金森叠加综合征患者进行运动和非运动症状、生活质量及功能表现评估。采用逻辑回归分析来研究后续2年内入院的预测因素。

结果

总体而言,162名患者同意参与本研究。71名帕金森症患者(43.8%)至少有1次入院记录,17名患者(10.5%)入院3次或更多次。认知功能较差、非运动症状较多、生活质量较差、计时起立行走测试得分较低以及吞咽异常可预测随后的入院情况。

讨论

我们的研究强调了非运动症状在预测入院方面的重要性。应考虑对预防入院的早期干预进行成本效益分析。

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