Kim Jeongin, Joh Jin Hyun, Park Ho-Chul
Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, Republic of Korea.
Exp Ther Med. 2019 Sep;18(3):1845-1849. doi: 10.3892/etm.2019.7758. Epub 2019 Jul 9.
Cyanoacrylate closure (CAC) has recently been introduced for the treatment of incompetent saphenous veins. The purpose of the present study is to investigate the correlation of the saphenous vein diameter and reflux time (RT) with the stump length after CAC. A retrospective review was performed using prospectively collected data of CAC patients. The pre-operative saphenous vein diameter and RT were measured. The stump length was measured immediately after the procedure and at 1 week. Pearson's correlation analysis was applied to determine the correlation between the saphenous vein diameter or RT and stump length. A total of 32 saphenous veins were closed in 21 patients, 15 of whom were female. The mean age was 56.9±12.6 years (range, 31-73 years). Complete closure was achieved in all patients. The pre-operative mean diameter was 7.0±2.2 mm. The mean stump lengths were 26.1±10.2 and 28.1±13.6 mm on post-operative days 0 and 7, respectively (P=0.002). The Pearson coefficients for the correlation between the saphenous vein diameter and stump length on post-operative days 0 and 7 were 0.528 (P=0.005) and 0.177 (P=0.430), respectively. Furthermore, the Pearson coefficients for the correlation between the RT and stump length on post-operative days 0 and 7 were -0.215 (P=0.282) and 0.019 (P=0.938), respectively. In conclusion, CAC is effective modality for the treatment of saphenous vein insufficiency. The stump length increased with the diameter of the saphenous veins, while the RT had no marked effect on the stump length. Therefore, the glue injection should be initiated from the instructed position to avoid glue extension into deep veins and to prevent elongating the stump length.
氰基丙烯酸酯封闭术（CAC）最近已被用于治疗大隐静脉功能不全。本研究的目的是探讨大隐静脉直径和反流时间（RT）与CAC术后残端长度的相关性。使用前瞻性收集的CAC患者数据进行回顾性分析。测量术前大隐静脉直径和RT。术后立即和术后1周测量残端长度。应用Pearson相关分析确定大隐静脉直径或RT与残端长度之间的相关性。21例患者共封闭了32条大隐静脉，其中15例为女性。平均年龄为56.9±12.6岁（范围31 - 73岁）。所有患者均实现完全封闭。术前平均直径为7.0±2.2 mm。术后第0天和第7天的平均残端长度分别为26.1±10.2和28.1±13.6 mm（P = 0.002）。术后第0天和第7天大隐静脉直径与残端长度之间的Pearson系数分别为0.528（P = 0.005）和0.177（P = 0.430）。此外，术后第0天和第7天RT与残端长度之间的Pearson系数分别为-0.215（P = 0.282）和0.019（P = 0.938）。总之，CAC是治疗大隐静脉功能不全的有效方法。残端长度随大隐静脉直径增加，而RT对残端长度无明显影响。因此，应从指定位置开始注射胶水，以避免胶水延伸至深静脉并防止残端长度延长。
