Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston.
Department of Radiation Medicine, Oregon Health & Science University, Portland.
JAMA Netw Open. 2019 Aug 2;2(8):e199135. doi: 10.1001/jamanetworkopen.2019.9135.
This survey study compares use of prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer before and after the publication of a phase 3 trial that demonstrated no overall survival benefit for this therapy.
这项调查研究比较了在一项三期临床试验发表前后,广泛期小细胞肺癌患者预防性颅脑照射的使用情况,该试验表明这种治疗方法对整体生存没有益处。