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广泛期小细胞肺癌预防性颅脑照射应用实践模式的演变。

Evolving Practice Patterns in the Use of Prophylactic Cranial Irradiation for Extensive-Stage Small Cell Lung Cancer.

机构信息

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston.

Department of Radiation Medicine, Oregon Health & Science University, Portland.

出版信息

JAMA Netw Open. 2019 Aug 2;2(8):e199135. doi: 10.1001/jamanetworkopen.2019.9135.

DOI:10.1001/jamanetworkopen.2019.9135
PMID:31411707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6694387/
Abstract

This survey study compares use of prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer before and after the publication of a phase 3 trial that demonstrated no overall survival benefit for this therapy.

摘要

这项调查研究比较了在一项三期临床试验发表前后，广泛期小细胞肺癌患者预防性颅脑照射的使用情况，该试验表明这种治疗方法对整体生存没有益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8be0/6694387/c1a8307de184/jamanetwopen-2-e199135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8be0/6694387/c1a8307de184/jamanetwopen-2-e199135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8be0/6694387/c1a8307de184/jamanetwopen-2-e199135-g001.jpg

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本文引用的文献

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J Oncol Pract. 2017 Nov;13(11):732-738. doi: 10.1200/JOP.2017.026765.
2
Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.广泛期小细胞肺癌患者预防性颅脑照射与观察的比较：一项多中心、随机、开放标签、3 期临床试验。
Lancet Oncol. 2017 May;18(5):663-671. doi: 10.1016/S1470-2045(17)30230-9. Epub 2017 Mar 23.
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Current Patterns of Care for Patients with Extensive-Stage SCLC: Survey of U.S. Radiation Oncologists on Their Recommendations Regarding Prophylactic Cranial Irradiation.
小细胞肺癌伴脑转移患者的治疗与生存。
J Neurooncol. 2023 Nov;165(2):343-351. doi: 10.1007/s11060-023-04512-2. Epub 2023 Nov 20.
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Comparison of first-line radiosurgery for small-cell and non-small cell lung cancer brain metastases (CROSS-FIRE).小细胞肺癌和非小细胞肺癌脑转移患者的一线立体定向放射外科治疗比较（CROSS-FIRE）。
J Natl Cancer Inst. 2023 Aug 8;115(8):926-936. doi: 10.1093/jnci/djad073.
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The overall survival impact of prophylactic cranial irradiation in limited-stage small-cell lung cancer: A systematic review and meta-analysis.预防性颅脑照射对局限期小细胞肺癌总生存的影响：一项系统评价和荟萃分析。
Clin Transl Radiat Oncol. 2022 Feb 17;33:145-152. doi: 10.1016/j.ctro.2022.02.002. eCollection 2022 Mar.
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Re-thinking about prophylactic cranial irradiation for small cell lung cancer in the MRI era.MRI时代小细胞肺癌预防性颅脑照射的再思考
J Thorac Dis. 2021 Aug;13(8):5115-5116. doi: 10.21037/jtd-21-870.
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