Berg W, Pirlich W, Kilian O
Department of Urology, Medical School, Friedrich Schiller University, Jena, GDR.
Eur Urol. 1988;14(6):458-63. doi: 10.1159/000473009.
The procedure described confirms that the Ni2+/S2O4(2-) tablet test is a suitable quick cystine screening test for large groups. In 16 (0.67%) of 2,395 one- to three-year-old crèche children significantly enhanced cystine levels of 0.60-0.96 mmol/l were found. The corresponding creatinine values (mmol/l) did not reveal any significant deviations from the normal values. In a preliminary group of 9 children, enhanced lysine levels support the suspicion of the existence of cystinuria without clinical symptoms. This also forms the basis for further necessary family histories as well as for prophylactic measures.
所描述的程序证实，Ni2+/S2O4(2-) 片剂试验是适用于对大群体进行快速胱氨酸筛查的测试。在2395名1至3岁托儿所儿童中，有16名（0.67%）被发现胱氨酸水平显著升高，为0.60 - 0.96 mmol/l。相应的肌酐值（mmol/l）与正常值相比未显示出任何显著偏差。在一个由9名儿童组成的初步群体中，赖氨酸水平升高支持了存在无症状胱氨酸尿症的怀疑。这也为进一步了解必要的家族病史以及采取预防措施奠定了基础。
