Department of Obstetrics and Gynecology, Busan Paik Hospital, Busan, Republic of Korea.
Paik Institute for Clinical Research, Busan Paik Hospital, Inje University, Busan, Republic of Korea.
J Matern Fetal Neonatal Med. 2021 Jul;34(13):2080-2088. doi: 10.1080/14767058.2019.1657085. Epub 2019 Aug 28.
This study aimed to compare obstetrical complications and neonatal outcomes between monochorionic and dichorionic discordant twin pregnancies.
We enrolled 296 patients with twin pregnancy who delivered at Busan Paik Hospital between January 2014 and December 2017. The prevalence of obstetrical complications, neonatal mortality between monochorionic and dichorionic twins was compared. We also investigated whether there is a difference in neonatal outcome and neonatal morbidity between monochorionic discordant twins without monochorionic-specific complications and dichorionic discordant twins.
The risk of fetal death (13.2 versus 5.2%, = .025) and inter twin birth weight discordance (35.1 versus 20.8%, = .031) is increased in monochorionic twins than in dichorionic twins. However, no difference was noted in obstetrical complication and neonatal mortality and morbidity between two groups. Among twin pregnancies with intertwin birth weight discordance, after excluding fetal death and monochorionic specific complication, there was no difference in obstetrical complication and neonatal mortality and morbidity according to chorionicity. There was no difference in neonatal morbidity between monochorionic twins and dichorionic twins when comparing larger neonates and smaller neonates of each group.
Risk of birth weight discordance is higher in monochorionic twin but no significant difference was observed in maternal outcomes, neonatal mortality and morbidity between noncomplicated monochorionic and dichorionic discordant twins.
本研究旨在比较单绒毛膜和双绒毛膜双胎妊娠的产科并发症和新生儿结局。
我们纳入了 2014 年 1 月至 2017 年 12 月在釜山 Paik 医院分娩的 296 例双胎妊娠患者。比较了单绒毛膜和双绒毛膜双胎妊娠的产科并发症发生率和新生儿死亡率。我们还研究了无单绒毛膜特有并发症的单绒毛膜双胎妊娠和双绒毛膜双胎妊娠之间的新生儿结局和新生儿发病率是否存在差异。
单绒毛膜双胎妊娠的胎儿死亡风险(13.2%比 5.2%, = .025)和双胎间出生体重差异(35.1%比 20.8%, = .031)高于双绒毛膜双胎妊娠。然而,两组间的产科并发症和新生儿死亡率及发病率无差异。在存在双胎间出生体重差异的双胎妊娠中,排除胎儿死亡和单绒毛膜特有并发症后,根据绒毛膜性,产科并发症和新生儿死亡率及发病率无差异。比较各组中较大和较小新生儿时,单绒毛膜双胎妊娠和双绒毛膜双胎妊娠的新生儿发病率无差异。
单绒毛膜双胎妊娠的体重差异风险较高,但在无并发症的单绒毛膜和双绒毛膜双胎妊娠之间,母婴结局、新生儿死亡率和发病率无显著差异。