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超声测量胎儿体重差异的双绒毛膜双羊膜囊双胎的孕妇并发症及新生儿结局预测。

Prediction of maternal complications and neonatal outcome in dichorionic diamniotic twins with fetal weight discordancy measured by ultrasonography.

机构信息

Department of Obstetrics and Gynecology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 41944, Daegu, Republic of Korea.

出版信息

Sci Rep. 2022 Sep 1;12(1):14889. doi: 10.1038/s41598-022-18864-8.

Abstract

This study aimed to determine the relationship between estimated fetal weight discordance by ultrasonography and maternal and neonatal outcomes in dichorionic diamniotic twin pregnancies. We conducted a retrospective review of the medical records of 106 twin pregnancies delivered at a single tertiary center between January 2011 and February 2020. At 20-24 and 28-32 weeks of gestation, participants were divided into two groups: discordant twins with an estimated fetal weight difference of more than 20% and concordant twins with a weight difference of less than 20%. Maternal complications and neonatal outcomes were compared between the two groups. Although the incidences of preeclampsia and placenta previa were significantly higher in discordant twins measured between 20 and 24 weeks, no statistical significance was found in neonatal outcomes. Delivery times were earlier, and neonatal weights were lower in discordant twins measured between 28 and 32 weeks. Neonatal outcomes such as ventilator use and neurodevelopment were also significantly different. Discordance in estimated fetal weight measured using ultrasonography between 20 and 24 weeks can be a risk factor for maternal preeclampsia and placenta previa, whereas discordance at 28-32 weeks may predict poor neonatal outcomes.

摘要

本研究旨在探讨超声估计胎儿体重差异与双绒毛膜双羊膜囊双胎母婴结局的关系。我们对 2011 年 1 月至 2020 年 2 月在一家三级中心分娩的 106 例双胎妊娠的病历进行了回顾性分析。在 20-24 周和 28-32 周时,将参与者分为两组:估计胎儿体重差异超过 20%的差异双胞胎组和体重差异小于 20%的一致双胞胎组。比较两组产妇并发症和新生儿结局。虽然在 20-24 周测量的差异双胞胎中,子痫前期和前置胎盘的发生率明显较高,但新生儿结局无统计学意义。在 28-32 周测量的差异双胞胎中,分娩时间更早,新生儿体重更低。呼吸机使用和神经发育等新生儿结局也有显著差异。在 20-24 周测量的超声估计胎儿体重差异可能是母体子痫前期和前置胎盘的危险因素,而在 28-32 周的差异可能预测新生儿结局不良。

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