Abdeltawab Adham Ahmed, Elmahmoudy Ahmed Mohamed, Elnammas Waeil, Mazen Amir
Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, EgyptEgypt.
J Saudi Heart Assoc. 2019 Oct;31(4):261-268. doi: 10.1016/j.jsha.2019.07.001. Epub 2019 Jul 17.
Right ventricular (RV) involvement in acute left ventricular (LV) myocardial infarction (MI) is frequently underestimated in the clinical setting owing to the diagnostic limitations of the electrocardiogram and echocardiography.
To assess RV function in patients presented with first acute anterior ST elevation myocardial infarction (STEMI) who underwent successful primary percutaneous coronary intervention (PCI) and factors affecting it.
Forty consecutive patients with anterior STEMI who underwent successful primary PCI were enrolled in the study. Presence of a coexisting clinical condition that might affect RV function, patients with RV infarction or those having significant stenosis (>50%) affecting RV branch or right coronary artery proximal to RV branch were excluded. Echocardiography was performed during the hospital stay to assess the LV and RV systolic and diastolic function with special focus on tricuspid annular plane systolic excursion, RV end-diastolic dimension, right atrial area, RV fractional area change, and tissue Doppler-derived myocardial performance index.
RV dysfunction according to our definition in the first anterior MI occurred in (55%) of the study population. Independent predictors for abnormal RV function were left circumflex artery mid or proximal affection, eventful procedure, occurrence of no reflow, glucose level, LV end-systolic dimension, LV end-diastolic dimension, and LV ejection fraction.
在临床环境中,由于心电图和超声心动图的诊断局限性,急性左心室(LV)心肌梗死(MI)时右心室(RV)受累情况常常被低估。
评估首次发生急性前壁ST段抬高型心肌梗死(STEMI)且接受成功的直接经皮冠状动脉介入治疗(PCI)患者的右心室功能及其影响因素。
连续纳入40例接受成功直接PCI的前壁STEMI患者。排除可能影响右心室功能的并存临床情况、右心室梗死患者或右心室分支或右冠状动脉近端有严重狭窄(>50%)的患者。住院期间行超声心动图检查,评估左心室和右心室的收缩及舒张功能,特别关注三尖瓣环平面收缩期位移、右心室舒张末期内径、右心房面积、右心室面积变化分数以及组织多普勒衍生的心肌做功指数。
根据我们的定义,在首次前壁心肌梗死患者中,55%的研究人群出现右心室功能障碍。右心室功能异常的独立预测因素为左旋支动脉中段或近端受累、手术复杂、发生无复流、血糖水平、左心室收缩末期内径、左心室舒张末期内径以及左心室射血分数。