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[Individualization of dose and fractionation of radiotherapy for head and neck cancers].

作者信息

Blanchard P, Biau J, Castelli J, Tao Y, Graff P, Nguyen F

机构信息

Département de radiothérapie oncologie, Gustave-Roussy Cancer Campus, 114, rue Édouard-Vaillant, 94800 Villejuif, France; Inserm, U1018 « Centre de recherche en épidémiologie et santé des populations » (CESP), 94800 Villejuif, France; Université Paris-Saclay, 94800 Villejuif, France.

Département de radiothérapie oncologie, centre Jean-Perrin, 63000 Clermont-Ferrand, France; Université Clermont-Auvergne, 63000 Clermont-Ferrand, France; Inserm, U1240 « Imagerie moléculaire et stratégies théranostiques » (Imost), 63000 Clermont-Ferrand, France.

出版信息

Cancer Radiother. 2019 Oct;23(6-7):784-788. doi: 10.1016/j.canrad.2019.07.131. Epub 2019 Aug 13.

DOI:10.1016/j.canrad.2019.07.131
PMID:31420129
Abstract

Head and neck cancers comprise a variety of tumours depending on the sub-site, for which target volumes and the prescribed doses need to be individualized according to each patient's history and presentation. This article aims at describing the main factors involved in decision-making regarding dose and volume, as well as ongoing research. Contouring and treatment guidelines, use of altered fractionation, major prognostic factors, the role of Human papillomavirus and of functional imaging will be presented and discussed.

摘要

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