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迷走传入神经的分子多样性揭示。

The Molecular Diversity of Vagal Afferents Revealed.

机构信息

Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Division of Hypothalamic Research and Department of Internal Medicine, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

出版信息

Trends Neurosci. 2019 Oct;42(10):663-666. doi: 10.1016/j.tins.2019.08.002. Epub 2019 Aug 14.

Abstract

Using single-cell RNA sequencing (RNA-seq), Kupari and coworkers (Cell Rep., 2019) have generated a long sought-after molecular atlas of vagal afferents in the mouse. Vagal afferents were found to be organized into 24 subtypes, revealing a level of diversity that was not previously recognized.

摘要

利用单细胞 RNA 测序(RNA-seq),Kupari 及其同事(Cell Rep.,2019)绘制了一张长期以来人们梦寐以求的小鼠迷走传入神经分子图谱。研究发现,迷走传入神经可分为 24 种亚型,揭示了此前未被识别的多样性水平。

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