An experimental model of tryptic haemorrhagic enteropathy of the dog.

To study the enteropathy characteristics of the shock state of the dog a simple experimental model has been developed. The cranial mesenteric artery was perfused with 2 micrograms/kg/min norepinephrine for an hour via a diagnostic cardiac catheter inserted under fluoroscopic control. This caused a "pharmacological occlusion" of the artery by local alpha receptor stimulation, and tryptic haemorrhagic enteritis was produced without hypovolaemia or assay operative procedure.